Cold Snare Versus Double Biopsy Polypectomy Technique for Removal of Diminutive Colorectal Polyps: a Prospective Randomized Trial
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 54
- 试验地点
- 2
- 主要终点
- Complete histologic polyp eradication rate
研究概览
简要总结
Most of colorectal polyps founded during colonoscopy are diminutive polyps less than 6 mm. However, complete removal of diminutive polyps is required to prevent tumor recurrence and development of potential interval cancers. Currently, a variety of polypectomy techniques such as hot snare, cold snare, and cold forceps polypectomy are frequently used for the removal of diminutive colorectal polyps. In regard to the completeness of polypectomy, there are few data comparing cold snare polypectomy with cold forceps biopsy technique for removal of diminutive (1-5 mm) colorectal polyps. The aim of this study is to compare cold snare polypectomy with cold forceps polypectomy using double biopsy technique for removal of diminutive colorectal polyps.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients over the age of 20
- •Informed consent
排除标准
- •Patient undergoing antiplatelets (aspirin, clopidogrel and others) or anticoagulant therapy
- •Known existing bleeding tendency (thrombocytopenia or prolonged INR)
- •Inflammatory bowel diseases (Crohn's disease, or ulcerative colitis)
- •ASA class III or more
- •Pregnancy
- •Any condition which, in the opinion of the Investigator, places the patient at unacceptable risk if he/she were to participate in the study
研究组 & 干预措施
Cold snare polypectomy
干预措施: removal of eligible polyps using cold snare polypectomy technique (Procedure)
Double biopsy polypectomy
干预措施: removal of eligible polyps using double biopsy technique (Procedure)
结局指标
主要结局
Complete histologic polyp eradication rate
时间窗: 2 weeks
次要结局
- Time taken for polypectomy (complete visual eradication of each polyp)(2 weeks)
- Successful tissue retrieval rate of removed tissues(2 weeks)
- Rates of adverse events(4 weeks)
- Complete visual polyp eradication rate(2 weeks)
研究者
Chang Kyun Lee
Assistant Professor
Kyunghee University Medical Center