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Clinical Trials/NCT06453629
NCT06453629
Completed
Not Applicable

A Randomized Controlled Study to Evaluate Social Skill Treatment Options in Children With Autism Using VR Technology

Floreo, Inc.34 sites in 1 country117 target enrollmentMay 31, 2024

Overview

Phase
Not Applicable
Intervention
Floreo VR
Conditions
Autism Spectrum Disorder
Sponsor
Floreo, Inc.
Enrollment
117
Locations
34
Primary Endpoint
Autism Impact Measure (AIM)
Status
Completed
Last Updated
26 days ago

Overview

Brief Summary

The goal of this randomized clinical trial is to compare and learn about Virtual Reality (VR) in children with autism/Autistic children.

The main question it aims to answer is:

• Does the Floreo VR clinical product show clinical improvement in autism symptoms?

Participants will engage the VR product for twice a week for twelve weeks.

They will be randomized to either the Floreo Clinical Product or a VR Control group experience.

Researchers will compare the two groups to see if there is an effect on learning specific skills and behaviors.

Detailed Description

The purpose of this study is to find out if Floreo's VR clinical program can help with autism symptoms such as social communication skills in autistic children. Recent advances in VR technology offers a new way to improve these types of skills in children with autism in an immersive and controlled environment. Questionnaires answered by adult caregivers will be used to assess the child's behaviors during the time of treatment. Clinician observations will also be conducted as a part of this study.

Registry
clinicaltrials.gov
Start Date
May 31, 2024
End Date
April 3, 2026
Last Updated
26 days ago
Study Type
Interventional
Study Design
Crossover
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Five to eighteen years old (inclusive) at the time of consent
  • Legal guardian is able and willing to properly sign and date informed consent indicating that they have been informed about the study and able to complete all visits \[If age appropriate, an assent will also be administered to the participant to inform them of the study and give them an opportunity to proceed or decline\]
  • Verified diagnosis of ASD documented by a qualified clinician according to DSM-V criteria
  • Receiving therapies at least two times per week in a clinic setting
  • Participant is able to complete and pass the VR orientation screening

Exclusion Criteria

  • Significant medical condition(s) \[examples listed below\] or other circumstances which, in the opinion of the treating clinician, would preclude compliance with the protocol, adequate cooperation in the study, or may prevent the participant from safely participating in the study:
  • Uncontrolled neurological conditions such as epilepsy, migraine
  • Current disorders affecting balance, such as vertigo
  • Primary sensory impairment such as blindness or deafness
  • Eye movement impairment, such as strabismus
  • Participants are enrolled in another clinical study
  • Participants known to be pregnant
  • Participation in this study is not in the best interest of the child, at the discretion of the treating clinician and the primary investigator.

Arms & Interventions

Floreo VR

Floreo VR is a 12 week program

Intervention: Floreo VR

VR Control

VR Control is a 12 week program that matches the Floreo VR interactions

Intervention: VR Control

VR Control Crossover

For participants who opt in, they will run the 12 week Floreo VR program

Intervention: Floreo VR

VR Control Crossover

For participants who opt in, they will run the 12 week Floreo VR program

Intervention: VR Control Crossover

Outcomes

Primary Outcomes

Autism Impact Measure (AIM)

Time Frame: Baseline-12 weeks

The primary objective of this study is to determine if administration of the Floreo VR compared to VR Control results in clinically significant improvement in autism symptoms as measured by the Autism Impact Measure (AIM) in the study participant population.

Secondary Outcomes

  • Assessment of Functional Living Skills (AFLS)(Baseline-12 weeks)
  • Child and Family Quality of Life (CFQL-2)(Baseline-12 weeks)
  • Total Autism Impact Measure (AIM) Score(baseline, 16 weeks, 20 weeks, 24 weeks)
  • Assessment of Functional Living Skills (AFLS)(baseline, 16 weeks, 20 weeks, 24 weeks)
  • Child and Family Quality of Life (CFQL-2)(baseline, 16, 20, and 24 weeks)

Study Sites (34)

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