The Role of 6% Hydroxyethyl starch and Ringers lactate for preloading in patients undergoing elective caesarean section under spinal anaesthesia
Phase 2
- Conditions
- Health Condition 1: O00-O9A- Pregnancy, childbirth and the puerperiumHealth Condition 2: O00-O9A- Pregnancy, childbirth and the puerperium
- Registration Number
- CTRI/2021/07/034758
- Lead Sponsor
- Government medical college Baroda
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
ASA I AND II
Exclusion Criteria
Unwillingness of the patient.
BMI >25kg/meter square, Height less than 152cms.
Patients with Multiple gestation.
Patients with spine deformity,previous history of spine surgeries.
Severe anemia,coagulation abnormalities and bleeding disorders.
Patients with active skin lesions over lumbosacral region.
Medical disorders like chronic hypertension,diabetes,liver disease,renal diseases(calculi,stenosis,altered renal function tests), and CVS abnormalities(MI,Heart blocks etc).
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the incidence of hypotension while using 6% HES or Ringers lactate for preloading who are undergoing elective caesarean section under spinal anaesthesia.Timepoint: To compare the incidence of hypotension while using 6% HES or Ringers lactate for preloading who are undergoing elective caesarean section under spinal anaesthesia. <br/ ><br>Patient will be monitored upto 24hrs after surgey
- Secondary Outcome Measures
Name Time Method To compare the requirement of ephedrine to treat hypotension when preloaded with 6%HES or ringers lactate. <br/ ><br>To assess the neonatal outcome in both the groups. <br/ ><br>To study the side effects of HES as well as complications of spinal anesthesia.Timepoint: Patients who develop hypotension will be treated with IV boluses of ephedrine and total requirements will be noted .Other side effects like bradycardia and allergic reactions will be noted and treated accordingly. <br/ ><br>allergic reactions to HES will be noted. <br/ ><br>Neonatal outcome will be maesured by APGAR score at 1st and 5th minute of delivery. <br/ ><br>Patients will be monitored postoperatively every 2hrly till 24hrs