Relationship Between Spinopelvic Parameters and Clinical Symptoms of Low-grade Lumbar Isthmic Spondylolisthesis: a Retrospective Analysis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 226
- 试验地点
- 1
- 主要终点
- PI
研究概览
简要总结
This was a retrospective study.PI and LL greatly influence IS and its progression. However, relationships between the spinopelvic parameters and clinical symptoms of patients with IS were not fully investigated in previous studies. Investigators hypothesized that spinopelvic parameters might be related to the clinical symptoms of IS patients. Therefore, the purpose of the present study was to investigate whether differences in spinopelvic parameters, especially spinopelvic alignment, may be associated with the clinical symptoms of low-grade IS patients.
详细描述
Isthmic spondylolisthesis (IS) is one of the most common types of spondylolisthesis, and spinopelvic parameters are closely related to the clinical symptoms of spinal diseases. In this study, investigators attempted to investigate the relationship between spinopelvic parameters and clinical symptoms of patients with low-grade (Meyerding grade I-II) isthmic spondylolisthesis (IS).
A total of 120 patients with low-grade IS and 106 asymptomatic adults were included in this study. Sex, age and body mass index (BMI) were also collected. Various spinopelvic parameters were evaluated in whole-spine standing-position X-rays. The following spinopelvic parameters were measured: pelvic incidence (PI), sacral slope (SS), pelvic tilt (PT) and lumbar lordosis (LL). The clinical symptoms of the IS patients were assessed with the Japanese Orthopaedic Association (JOA) score and the visual analogue scale (VAS). Investigators compared spinopelvic parameters between the asymptomatic adults and the IS patients. Additionally, investigators investigated correlations between spinopelvic parameters and clinical symptoms.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 54 Years 至 76 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •isthmic spondylolisthesis subjects had spondylolisthesis at L4 or L5 (Meyerding grade I-II) with whole-spine standing lateral images
排除标准
- •spondylolisthesis of other types (Degenerative, dysplastic, etc.);
- •Lumbar infection and/or tumor diseases;
- •A previous history of lumbar fusion surgery.
研究组 & 干预措施
IS GROUP
Patients who received an operation to treat their isthmic spondylolisthesis (IS, Meyerding grade I-II)
干预措施: PI-LL (Radiation)
AS GROUP
The asymptomatic adults had no history of severe back pain or spinal trauma
结局指标
主要结局
PI
时间窗: through study completion, an average of 1 year
pelvic incidence
SS
时间窗: through study completion, an average of 1 year
sacral slope
PT
时间窗: through study completion, an average of 1 year
pelvic tilt
LL
时间窗: through study completion, an average of 1 year
lumbar lordosis
PI-LL
时间窗: through study completion, an average of 1 year
pelvic incidence minus lumbar lordosis
次要结局
- VAS(through study completion, an average of 1 year)
- JOA(through study completion, an average of 1 year)