Effect of Deep Brain Stimulation on Lower Urinary Tract Function

Not Applicable

Completed

• Conditions: Movement Disorder; Urinary Tract Disease
• Interventions: Procedure: Deep brain stimulation OFF; Procedure: deep brain stimulation ON

• Registration Number: NCT00610233
• Lead Sponsor: Insel Gruppe AG, University Hospital Bern

Brief Summary

The precise mechanisms underlying cerebral regulation of lower urinary tract (LUT) function are still poorly understood. Patients with deep brain stimulation (DBS) offer the unique opportunity to investigate the role of different cerebral centers on LUT function.

We hypothesize that DBS has a significant effect on LUT function and that these effects depend on the specific stimulated cerebral center.

Detailed Description

Not available

Study Timeline

• Study Start: 2005-06
• Study First Submitted: 2008-01-24
• Study First Submitted QC: 2008-02-06
• Study First Posted: 2008-02-07
• Primary Completion: 2014-06
• Study Completion: 2014-06
• Status Verified: 2014-09
• Last Update Submitted: 2014-09-18
• Last Update Posted: 2014-09-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 45

Inclusion Criteria

• Patients with deep brain stimulation (DBS)

Exclusion Criteria

• Pregnancy
• Age <18 years

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
B	Deep brain stimulation OFF	Urodynamics with deep brain stimulation OFF
A	deep brain stimulation ON	Urodynamic investigation with deep brain stimulation ON

Primary Outcome Measures

Name	Time	Method
Effect of deep brain stimulation (DBS) on urodynamic parameters	immediately and 3 months after study inclusion

Secondary Outcome Measures

Name	Time	Method
Changes in questionnaire data due to deep brain stimulation (DBS)	3 months

Trial Locations

Locations (2)

Department of Neurology, University of Bern; 🇨🇭 Bern, Switzerland

Department of Urology, University of Bern; 🇨🇭 Bern, Switzerland