Efficacy of Poststroke Intensive Rosuvastatin Treatment for Aortogenic Embolic Stroke (EPISTEME trial)
Not Applicable
- Conditions
- Brain infarction or transient ischemic attack with atheromatous plaques in the aortic arch
- Registration Number
- JPRN-UMIN000010548
- Lead Sponsor
- Department of Neurology, Juntendo Universiy School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
Not provided
Exclusion Criteria
1) Patients during pregnancy or lactation 2) Allergy against statin 3) Patients with coronary artery disease and requiring statin therapy 4) Patients with severe renal dysfunction or liver dysfunction 5) Patients undergoing cyclosporin therapy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Morphological alteration of atheromatous plaques in the aortic arch
- Secondary Outcome Measures
Name Time Method 1) Alteration of atheromatous plaques in the aortic arch 2) Changes in lipid profile 3) Changes in inflammatory markers and white blood cell count 4) Recurrence of ischemic stroke 5) Prevalence of hemorrhagic stroke including intracranial brain hemorrhage and subarachnoid hemorrhage 6) Prevalence of coronary artery disease 7) Other vascular diseases 8) Death