Early initiation of intra pleural streptokinase therapy versus placebo in the treatment of complicated pleural effusion in pediatric; An experience in tertiary care hospital.
Phase 3
- Conditions
- This study will be helpful in managing patients with complicated parapneumonic effusion by early intervention with instillation of intrapleural streptokinase.Intrapleural streptokinase, complicated pleural effusion, children
- Registration Number
- TCTR20240411001
- Lead Sponsor
- The Children's Hospital Lahore & University of Child Health Sciences Lahore
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending (Not yet recruiting)
- Sex
- All
- Target Recruitment
- 62
Inclusion Criteria
All children presented with stage II complicated pleural effusion/ empyema with age range of 6 months to 15 years, that fails to resolve by simple drainage by chest tube thoracotomy over 24 hours of admission.
Exclusion Criteria
Children having
1.Disseminated intravascular coagulation.
2.Volume overload.
3.Allergic/ hypersensitivity to streptokinase
4.Consent withdrawal.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method eed of surgical intervention for complicated pleural effusion 6 months Chi square test
- Secondary Outcome Measures
Name Time Method length of stay in the hospital 6 months chi square test