Comparison of Using Collagen Membrane and A-PRF Using VISTA Technique in Gingival Recession Treatment

Not Applicable

Active, not recruiting

• Conditions: Gingival Recession

• Registration Number: NCT06357351
• Lead Sponsor: Mansoura University

Brief Summary

To assess the efficacy of minimally invasive Vestibular Incision Subperiosteal Tunnel Access (VISTA) with collagen membrane and Advanced Platelet-rich Fibrin (A-PRF) in the treatment of multiple buccal gingival recession type 1(RT1) Cairo Classification.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-07-01
• Status Verified: 2024-04
• Primary Completion: 2024-04
• Study First Submitted: 2024-04-04
• Study First Submitted QC: 2024-04-09
• Last Update Submitted: 2024-04-09
• Study First Posted: 2024-04-10
• Last Update Posted: 2024-04-10
• Study Completion: 2024-05

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

• (18-50) years old with at least 2 sites with gingival recession type (RT1) Cairo Classification (GR with no interdental attachment loss). The interdental CEJ is not detectable clinically on the labial surfaces of the teeth.
• Recession in the maxillary anterior region ≥1 mm of attached gingiva, pocket depth (PD) of <3 mm, recession depth (RD) ≥2 mm, and gingival index (GI) score ≤1.
• Systemically healthy, willing individuals with good oral hygiene and without contraindications for surgical interventions

Exclusion Criteria

• the presence of severe systematic diseases or immunodeficiency and contraindicated with surgical interventions.
• Allergies to medicaments used in the treatment process.
• Patients with removable or fixed dentures.
• Patients with cervical abrasion, direct and indirect restorations involving the cervical areas of the maxillary anterior.
• Participants with smoking, tobacco chewing, and alcohol consumption.
• The presence of high frenal attachment and participants who had previously undergone any periodontal surgical procedure or regenerative therapy in the past 1 year at the same site of the planned treatment.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Measuring the recession width in millimeter	baseline, 3 months and 6 months	self-report assessment by using the UNC-15 Periodontal Probe, measured at the level of Cemento-Enamel Junction CEJ.
Measuring the recession depth in millimeter	baseline, 3 months and 6 months	self-report assessment by using the UNC-15 Periodontal Probe, measured from the cemento-enamel junction CEJ to the free gingival junction.
Measuring the width of keratinized gingiva in millimeter	baseline, 3 months and 6 months	self-report assessment by using the UNC-15 Periodontal Probe. measured from the free gingiva margin to the mucogingival junction.
Mean of root coverage	baseline, and 6 months	was measured by the following formula:. Mean root coverage formula: (pre-operative recession depth - post-operative recession depth)/(pre-operative recession depth ) ×100

Secondary Outcome Measures

Name	Time	Method
Measuring the probing depth	baseline, 3 months and 6 months	self-report assessment by using the UNC-15 Periodontal Probe. Measured from the free gingival margin to the base of the sulcus.
Measuring the plaque index	baseline, 3 months and 6 months	According to Silness and Leo, this index determines the thickness of the plaque along the gingival margin. possible score range from 0 (no plaque) to 1 ( thin plaque located at gingival margin only detected by periodontal probe), 2 ( moderate plaque thickness detected by naked eye located at gingival margin), and 3 ( abundant plaque thickness at gingival margin and interproximal area)
Measuring the gingival index	baseline, 3 months and 6 months	According to Silness and Leo, this index determines the description of the gingiva of examined teeth. possible score range from 0 (normal gingiva) to 1 (mild inflammation; slight erythema; no bleeding.) / 2 (moderate inflammation; erythema and bleeding on probing) or 3 (severe inflammation; severe erythema, swelling, and spontaneous bleeding).
Clinical attachment level	baseline, 3 months and 6 months	self-report assessment by using the UNC-15 Periodontal Probe, measured from the cemento-enamel junction to the base of the pocket.

Trial Locations

Locations (1)

Mansoura university; 🇪🇬 Mansoura, Egypt