Minimally invasive surfactant therapy and diaphragm activity in preterm infants

Completed

• Conditions: Respiratory distress syndrome; respiratory problems of newborn preterm infants; 10028971

• Registration Number: NL-OMON46170
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 20

Inclusion Criteria

- Born at gestational age < 37 weeks
- Non-invasive respiratory support
- Clinical signs of RDS in first 72 hours after birth
- Indication for MIST based on our hospital protocol and ascertained by the attending physician
- Written parental consent

Exclusion Criteria

- Major congenital anomalies
- The attending physician considers the infant to be too vulnerable to participate in the study

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Changes in electrical activity of the diaphragm after MIST</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Changes in Vt after MIST<br /><br>The correlation of changes in diaphragm activity and changes in Vt after MIST. </p><br>