Comparison of Sugammadex and Neostigmine for Time to Extubation in Adult Patients Undergoing Routine Ophthalmic Surgery Under General Anesthesia
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 262
- 试验地点
- 1
- 主要终点
- Time From reversal to extubation
研究概览
简要总结
This study is to invastigate if patients treated with sugammadex compared to neostigmine/atropine would be extubate faster upon emergence of anesthesia.
详细描述
This is a retrospective case-control study including patients aged 18 years or older who underwent ophthalmic surgeries under general anesthesia with tracheal intubation between 2020 and 2022. Patients who received rocuronium as the sole neuromuscular blocking agent and were maintained with sevoflurane or desflurane and intravenous fentanyl were included. Based on the choice of reversal agent for neuromuscular blockade, patients were divided into two groups: the sugammadex group or the neostigmine group. Patients who underwent emergency surgery or combined surgeries with other specialties were excluded. Patient characteristics, including age, gender, ASA classification, weight, and height, were collected. Anesthesia-related medications were recorded. The time points of anesthesia induction, start and end of surgery, reversal agent administration, and tracheal extubation were documented.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •aged 18 years or older ophthalmic surgeries under general anesthesia with tracheal intubation between 2020 and 2022 received rocuronium as the sole neuromuscular blocking agent maintained with sevoflurane or desflurane and intravenous fentanyl
排除标准
- •emergency surgery combined surgeries with other specialties
研究组 & 干预措施
sugammadex
those who use sugammadex for reversal of neuromuscular blockade
干预措施: sugammadex (Drug)
neostigmine
those who use neostigmine/atroping for reversal of neuromuscular blockade
干预措施: Neostigmine + Atropine (Drug)
结局指标
主要结局
Time From reversal to extubation
时间窗: Time From reversal to extubation
Time From reversal to extubation
Time From the end of surgery to reversal
时间窗: Time From the end of surgery to reversal
Time From the end of surgery to reversal
次要结局
- Time From induction to the end of surgery(Time From induction to the end of surgery)
