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临床试验/NCT06632067
NCT06632067已完成不适用

Comparison of Sugammadex and Neostigmine for Time to Extubation in Adult Patients Undergoing Routine Ophthalmic Surgery Under General Anesthesia

China Medical University Hospital1 个研究点 分布在 1 个国家目标入组 262 人开始时间: 2023年8月1日最近更新:
适应症
干预措施
相关药物

试验速览

阶段
不适用
状态
已完成
入组人数
262
试验地点
1
主要终点
Time From reversal to extubation

研究概览

简要总结

This study is to invastigate if patients treated with sugammadex compared to neostigmine/atropine would be extubate faster upon emergence of anesthesia.

详细描述

This is a retrospective case-control study including patients aged 18 years or older who underwent ophthalmic surgeries under general anesthesia with tracheal intubation between 2020 and 2022. Patients who received rocuronium as the sole neuromuscular blocking agent and were maintained with sevoflurane or desflurane and intravenous fentanyl were included. Based on the choice of reversal agent for neuromuscular blockade, patients were divided into two groups: the sugammadex group or the neostigmine group. Patients who underwent emergency surgery or combined surgeries with other specialties were excluded. Patient characteristics, including age, gender, ASA classification, weight, and height, were collected. Anesthesia-related medications were recorded. The time points of anesthesia induction, start and end of surgery, reversal agent administration, and tracheal extubation were documented.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • aged 18 years or older ophthalmic surgeries under general anesthesia with tracheal intubation between 2020 and 2022 received rocuronium as the sole neuromuscular blocking agent maintained with sevoflurane or desflurane and intravenous fentanyl

排除标准

  • emergency surgery combined surgeries with other specialties

研究组 & 干预措施

sugammadex

those who use sugammadex for reversal of neuromuscular blockade

干预措施: sugammadex (Drug)

neostigmine

those who use neostigmine/atroping for reversal of neuromuscular blockade

干预措施: Neostigmine + Atropine (Drug)

结局指标

主要结局

Time From reversal to extubation

时间窗: Time From reversal to extubation

Time From reversal to extubation

Time From the end of surgery to reversal

时间窗: Time From the end of surgery to reversal

Time From the end of surgery to reversal

次要结局

  • Time From induction to the end of surgery(Time From induction to the end of surgery)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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