NCT00606385Unknown不适用
Prospective Randomized Trial of Laparoscopic Versus Open Liver Resection for Patients With Hepatocellular Carcinoma
适应症
干预措施
试验速览
- 阶段
- 不适用
- 入组人数
- 84
- 试验地点
- 1
- 主要终点
- Recurrence rate
研究概览
简要总结
Short-term outcomes of laparoscopic liver resection is better than those of open liver resection
Laparoscopic liver resection is better than open resection in immunological aspects
详细描述
Advantages and disadvantages of the laparoscopic compared with the open approach for liver resections
- Advantages 1) Less postoperative ascites production 2) Reduced postoperative pain 3) Feasible in selected cirrhotics who have contraindications to open surgery 4) Less intra-abdominal adhesions (easier salvage transplantation) 5) Shorter recovery time 6) Shorter length of stay 7) Reduced financial cost
- Disadvantages 1) No manual palpation or exploration of the liver parenchyma possible (with the pure laparoscopic approach) 2) High demand in surgical skill (especially major resections)
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Radiologically diagnosed hepatocellular carcinoma
- •Child classification A or B
- •Aged 20 to 80
- •Informed consent taken
排除标准
- •Child classification C
- •Extrahepatic metastasis
- •Tumor located in central area or adjacent to middle hepatic vein
- •Recurred hepatocellular carcinoma
- •Critically ill patient
- •Patient with psychiatric disease
研究组 & 干预措施
laparoscopic liver resection
Experimental
Patients who underwent laparoscopic liver resection for HCC
干预措施: Liver resection (Procedure)
open liver resection
Active Comparator
Patients who underwent open liver resection for HCC
干预措施: Liver resection (Procedure)
结局指标
主要结局
Recurrence rate
时间窗: 2 years after operation
次要结局
- Survival(2 years after operation)
研究者
Ho-Seong Han
Professor
Seoul National University Hospital
研究点 (1)
Loading locations...
相似试验
Unknown
不适用
Oslo Randomized Laparoscopic Versus Open Liver Resection for Colorectal Metastases StudySecondary Malignant Neoplasm of LiverColorectal NeoplasmsNCT01516710Oslo University Hospital280
已完成
不适用
Laparoscopic Hepatectomy Versus Open Hepatectomy for PHCPrimary Liver CarcinomaNCT02014025Shuguo Zheng, MD335
Unknown
不适用
Open Versus Laparoscopic Left Hepatic SectionectomyHepatolithiasisLaparoscopic Liver ResectionOpen Liver ResectionEnhanced RecoveryNCT03958825The Second Hospital of Anhui Medical University88
Unknown
不适用
Comparison of Laparoscopic Versus Open Gastrectomy for Advanced Gastric Cancer:A Prospective Randomized TrialStomach NeoplasmLaparoscopyGastrectomyComplicationsNCT01043835Yan Shi328
Unknown
不适用
Laparoscopic Versus Open Liver Resection in the Treatment of Hepatocellular CarcinomaHepatocellular CarcinomaNCT01768741Sir Run Run Shaw Hospital500