The DAMA Trial: a physical activity and diet intervention trial to reduce mammographic breast density, a strong risk factor for breast cancer, in postmenopausal women - a factorial randomized trial

Cancer Research and Prevention Institute (ISPO) (Italy)0 个研究点目标入组 234 人开始时间: 2012年5月17日最近更新: 2023年1月9日

适应症

试验速览

2014 Results article in http://www.ncbi.nlm.nih.gov/pubmed/25296586 results 2019 Results article in https://pubmed.ncbi.nlm.nih.gov/30068518/ results (added 16/12/2020) 2022 Other publications in https://pubmed.ncbi.nlm.nih.gov/36454365/ (added 02/12/2022)

•Postmenopausal women aged 50-69 years, with a high-density mammographic pattern as routinely assessed in the local screening program by a semi-quantitative method (> 50% high-density area)

•1. Pre- or peri-menopausal status
•2. Current or recent (last 12 months) hormone replacement therapy
•3. Current smokers
•4. Diabetes and/or other major co-morbidities that could affect the possibility to follow the intervention protocol (major cardiovascular diseases, severe hip or knee osteoarthritis)
•5. Previous diagnosis of breast cancer or other malignancies

发起方

Cancer Research and Prevention Institute (ISPO) (Italy)