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Bacillus Calmette Guerin (BCG) vaccination/revaccination for prevention of Mycobacterium tuberculosis infection in healthcare students entering clinical training: A randomised placebo controlled proof of principle trial (PoP BCG trial)

Not Applicable
Active, not recruiting
Conditions
Infection
tuberculosis
Infection - Studies of infection and infectious agents
Registration Number
ACTRN12619001327178
Lead Sponsor
niversity of Otago
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Active, not recruiting
Sex
All
Target Recruitment
150
Inclusion Criteria

1.Medical or nursing students who start their clinical training at Hasan
Sadikin Hospital
2.Tested IGRA negative at screening
3.Tested HIV negative at screening
4.Completed the written informed consent

Exclusion Criteria

1.Retraining nursing students (retraining to transform their nursing
qualification into a degree)
2.A positive prior tuberculin skin test (TST) and/or IGRA
3.A history of treatment for TB disease or latent TB infection
4.A history or evidence of TB disease
5.For female students: currently pregnant or lactating/nursing; or positive
urine pregnancy test during screening
6.History of autoimmune disease or immunosuppression or used
immunosuppressive medication

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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