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Precision medicine and personalized care in patients with rotator cuff disease: future perspectives and new frontiers using machine learning models

Not Applicable
Conditions
Rotator cuff tears
Musculoskeletal Diseases
Registration Number
ISRCTN13188760
Lead Sponsor
Fondazione Policlinico Universitario Campus Bio-Medico
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Ongoing
Sex
All
Target Recruitment
100
Inclusion Criteria

1. Age 40-75 years
2. Rotator cuff tears documented with MRI
3. No surgical treatment to the affected shoulder before
4. No episodes of shoulder instability
5. No radiographic signs of fracture of the glenoid fossa or the greater or lesser tuberosity

Exclusion Criteria

1. Frozen shoulder
2. Radiological osteoarthritis of the glenohumeral joint
3. Neurological disease or language barriers
4. Impossibility to undergo an MRI scan for any reason

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Structural tendon integrity, as evidenced by MRI evaluations at 12 months after surgery
Secondary Outcome Measures
NameTimeMethod
Measured before and after surgery:<br>1. Kinematic variables (such as range of motion, angular velocity) measured by kinematic analysis<br>2. Physical and subjective measures of the affected shoulder in terms of pain, activities of daily living (ADL), range of motion (ROM), and strength measured by the Constant-Murley score (CMS)<br>3. Patient self-reported and clinician scores about pain, ADL, ROM, signs, strength, and instability measured by the American Shoulder and Elbow Surgeons (ASES) score<br>4. Quality of life and mental health (such as physical and social functioning, general health perception limitations due to emotional aspects, vitality) measured by SF-36<br>5. The level of pain perceived by patients measured by visual analogue score (VAS)
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