Comparison of the Effects of Perioperative Anesthesia Consumption of Ultrasound Guided Subcostal Transversus Abdominis Plane and Paravertebral Block in Laparoscopic Cholecystectomy
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Cholecystitis
- Sponsor
- Cukurova University
- Enrollment
- 50
- Primary Endpoint
- anesthetic and opioid consumption during operation
- Status
- Completed
- Last Updated
- 11 years ago
Overview
Brief Summary
The investigators aimed to compare the effects of perioperative anesthesia consumption of ultrasound guided subcostal transversus abdominis plane and paravertebral block in laparoscopic cholecystectomy.
Detailed Description
Fifty patients aged 18 - 65 years, American Society of Anesthesiologists (ASA) I-II-III, scheduled for laparoscopic cholecystectomy were enrolled into the study. Patients were allocated into two groups to receive ultrasound guided subcostal transversus abdominis plane block (group T, n=25) or ultrasound guided paravertebral block (group P, n=25). In all patients; anesthesia was induced with iv propofol (2 mg.kg-1) and maintained with total intravenous anesthesia (TIVA) in a mixture of 50 % nitrous oxide and 50 % oxygen with a total gas flow rate of 4 L min-1. Neuromuscular relaxation was induced with iv rocuronium (0.5 mg.kg-1). Propofol (2 mg / cc, 2-4 mg / kg / h) and remifentanil (13.3 mcg / cc, 1-3 mcg / kg / h) combination was used in TIVA. Propofol and remifentanil rates increased or reduced according to the patient's hemodynamic response. Prior to start surgery, ultrasound guided subcostal transversus abdominis plane or paravertebral block was performed in patients . Blood pressure, heart rate and peripheral oxygen saturation,TIVA consumption of 0, 5, 10, 15, 30, 60 min were recorded for all patients.Before the end of surgery, tramadol was administered (2 mg / kg) for all patients. All patients were evaluated at postoperative 2th, 4th, 8th, 12th, 24th hours with; operation time, heart rate, blood pressure, peripheral oxygen saturation, visual pain scores (VAS), analgesic consumption, complications (hypotension, anaphylaxis, hematoma, IV injection, intra-abdominal organ injury, pneumothorax ) and patient satisfaction status were recorded. In the postoperative period if there is additional analgesic requirements (VAS≥4) tramadol 2 mg.kg-1 was administered as IV. The first hour is needed analgesia were recorded.
Investigators
ILKE KUPELI
specialist dr
Cukurova University
Eligibility Criteria
Inclusion Criteria
- •Between 18-65 years of age,
- •ASA I-II-III
- •laparoscopic cholecystectomy to be applied
Exclusion Criteria
- •patient refusal
- •mental and psychiatric disorders,
- •allergy history of the drug to be used,
- •kyphoscoliotic anatomical disorder
- •patients with coagulopathies
Outcomes
Primary Outcomes
anesthetic and opioid consumption during operation
Time Frame: six months
Secondary Outcomes
- postoperative VAS scores(six months)
- duration of analgesia(six months)