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Clinical Trials/NCT02379780
NCT02379780
Completed
N/A

Comparison of the Effects of Perioperative Anesthesia Consumption of Ultrasound Guided Subcostal Transversus Abdominis Plane and Paravertebral Block in Laparoscopic Cholecystectomy

Cukurova University0 sites50 target enrollmentSeptember 2014
ConditionsCholecystitis

Overview

Phase
N/A
Intervention
Not specified
Conditions
Cholecystitis
Sponsor
Cukurova University
Enrollment
50
Primary Endpoint
anesthetic and opioid consumption during operation
Status
Completed
Last Updated
11 years ago

Overview

Brief Summary

The investigators aimed to compare the effects of perioperative anesthesia consumption of ultrasound guided subcostal transversus abdominis plane and paravertebral block in laparoscopic cholecystectomy.

Detailed Description

Fifty patients aged 18 - 65 years, American Society of Anesthesiologists (ASA) I-II-III, scheduled for laparoscopic cholecystectomy were enrolled into the study. Patients were allocated into two groups to receive ultrasound guided subcostal transversus abdominis plane block (group T, n=25) or ultrasound guided paravertebral block (group P, n=25). In all patients; anesthesia was induced with iv propofol (2 mg.kg-1) and maintained with total intravenous anesthesia (TIVA) in a mixture of 50 % nitrous oxide and 50 % oxygen with a total gas flow rate of 4 L min-1. Neuromuscular relaxation was induced with iv rocuronium (0.5 mg.kg-1). Propofol (2 mg / cc, 2-4 mg / kg / h) and remifentanil (13.3 mcg / cc, 1-3 mcg / kg / h) combination was used in TIVA. Propofol and remifentanil rates increased or reduced according to the patient's hemodynamic response. Prior to start surgery, ultrasound guided subcostal transversus abdominis plane or paravertebral block was performed in patients . Blood pressure, heart rate and peripheral oxygen saturation,TIVA consumption of 0, 5, 10, 15, 30, 60 min were recorded for all patients.Before the end of surgery, tramadol was administered (2 mg / kg) for all patients. All patients were evaluated at postoperative 2th, 4th, 8th, 12th, 24th hours with; operation time, heart rate, blood pressure, peripheral oxygen saturation, visual pain scores (VAS), analgesic consumption, complications (hypotension, anaphylaxis, hematoma, IV injection, intra-abdominal organ injury, pneumothorax ) and patient satisfaction status were recorded. In the postoperative period if there is additional analgesic requirements (VAS≥4) tramadol 2 mg.kg-1 was administered as IV. The first hour is needed analgesia were recorded.

Registry
clinicaltrials.gov
Start Date
September 2014
End Date
February 2015
Last Updated
11 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

ILKE KUPELI

specialist dr

Cukurova University

Eligibility Criteria

Inclusion Criteria

  • Between 18-65 years of age,
  • ASA I-II-III
  • laparoscopic cholecystectomy to be applied

Exclusion Criteria

  • patient refusal
  • mental and psychiatric disorders,
  • allergy history of the drug to be used,
  • kyphoscoliotic anatomical disorder
  • patients with coagulopathies

Outcomes

Primary Outcomes

anesthetic and opioid consumption during operation

Time Frame: six months

Secondary Outcomes

  • postoperative VAS scores(six months)
  • duration of analgesia(six months)

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