NCT03072615已完成不适用
Role of SWE-change After TIPS in the Prediction of Prognosis After TIPS
Jonel Trebicka0 个研究点目标入组 83 人开始时间: 2013年4月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 83
- 主要终点
- Survival
研究概览
简要总结
The aim of our prospective multicenter study was to investigate the prognostic value of the acute and long-term changes of liver stiffness in patients receiving a transjugular intrahepatic portosystemic shunt (TIPS).
详细描述
We included 83 patients receiving TIPS for prevention of rebleeding, therapy-refractory ascites or both. Hemodynamic parameters were assessed before TIPS and after TIPS insertion. 16 patients from Freiburg underwent TE immediately before and after TIPS. In 67 patients from Bonn, SWE of liver and spleen, as well as clinical and biochemical parameters were assessed before TIPS, seven days and six weeks after TIPS.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •TIPS insertion and had reliable SWE or TE measurement
排除标准
- •contraindication for TIPS
- •no reliable SWE or TE measurement
结局指标
主要结局
Survival
时间窗: 3 months
次要结局
- Acute-on-chronic Lvier failure(3 months)
研究者
Jonel Trebicka
Prof. Dr.
University Hospital, Bonn
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