Objective Evaluation of Cerebral Venous Sinus Attenuation on NCCT Brain and its Correlation with Haematological Parameters in Anemic Patients
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 55
- 试验地点
- 1
- 主要终点
- A significant correlation between attenuation values on NCCT brain and laboratory hemoglobin and hematocrit levels
研究概览
简要总结
Non-contrast computed tomography NCCT of the brain is a rapid, widely available imaging tool that can provide indirect information about blood composition through cerebral venous sinus attenuation. Hemoglobin and hematocrit levels directly influence attenuation values, with anemia leading to physiologically reduced density that may mimic pathology, potentially resulting in diagnostic errors. This prospective observational cross-sectional study aims to objectively measure Hounsfield Unit values of major cerebral venous sinuses such as the superior sagittal and transverse sinuses in adult anemic patients and correlate these findings with hematological parameters obtained within 24 hours of imaging. By establishing reference attenuation ranges specific to anemia, the study seeks to improve the accuracy of NCCT interpretation, reduce false-positive diagnoses, and enhance decision making in emergency and resource-limited settings.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 90.00 Year(s)(—)
- 性别
- All
入选标准
- •1.Diagnosed with anemia based on WHO criteria hemoglobin less than 13 gms per dal for males, less than 12 gms per dal for females.
- •Underwent NCCT brain within 24 hours of complete blood count.
排除标准
- •1.Presence of intracranial hemorrhage, intracranial surgery, polytrauma, mass lesion, or significant artifact on CT affecting sinus evaluation.
- •History of recent blood transfusion within the past 72 hours.
- •Pregnant patients.
结局指标
主要结局
A significant correlation between attenuation values on NCCT brain and laboratory hemoglobin and hematocrit levels
时间窗: Assessment will be done at 8 weeks
次要结局
未报告次要终点
研究者
DrPriyanka Sanil
Datta Megha Institute of Higher Education and Research
