Safety-Consumption and Cholesterol-Lowering Effects of Lactobacillus paracasei TISTR 2593 by the Alternating Cholesterol Metabolism and Parameters Associated with Atherosclerosis in Hypercholesterolemic Subjects

Thailand Institute of Scientific and Technological Research (TISTR)0 个研究点目标入组 22 人开始时间: 2022年9月17日最近更新: 2024年8月19日

适应症

试验速览

阶段: 1 期
状态: 已完成
发起方
入组人数: 22

研究概览入排标准研究者记录与标识符相似试验

研究概览

简要总结

Placebo group shows TC (231.48, 252.13, 267.70), TG (146.09, 157.96, 157.14) HDL-c (52.48, 58.65, 57.00), LDL-c (151.61, 161.87,163.00), MDA (0.071, 0.064, 0.078), TNF-alpha (11.541, 12.882,9.759), ApoE (0.783, 0.817, 0.806) (0, 45, 90 days). L. paracasei TISTR 2593 shows TC (233.50, 224.90, 277.75), TG (143.50, 153.60, 151.21) HDL-c (53.35, 56.75, 55.85), LDL-c (155.15, 137.40, 137.63), MDA (0.069, 0.045, 0.030), TNF-alpha (11.163, 9.656, 6.063), ApoE (0.751, 0.872, 0.887) (0, 45, 90 days).

研究设计

研究类型: Interventional

入排标准

年龄范围: 30 Years 至 65 Years（—）
性别: All

入选标准

•Subjects were eligible for the study both male and female (non-pregnant), aged 30 to 65 years, mild and modulate hypercholesterolemia, BMI between 19 and 30 kg/m2, no a vegan and vegetarian and no cholesterol and triglycerides lowering drug.

排除标准

•In the case of a previous cardiovascular event within the last 6 months, the presence of secondary dyslipaemias.

研究者

发起方

Thailand Institute of Scientific and Technological Research (TISTR)

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