Role of 18F-FDG PET/CT in the Evaluation of Cavernous Sinus Syndrome: a Pilot Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 54
- 试验地点
- 1
- 主要终点
- SUVmax of the cavernous sinus lesions on FDG PET/CT
研究概览
简要总结
Cavernous sinus syndrome (CSS) can be caused by a wide range of inflammatory, malignant, benign, vascular and miscellaneous disorders. Even after modern advances, reaching the final etiological diagnosis remains a challenge in CSS. This study is planned to determine the role and incremental value of 18F-FDG PET/CT in characterising different cavernous sinus pathologies based on their metabolic activity and detecting extracranial involvement.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with age greater than or equal to 18 years,
- •with newly diagnosed CSS,
- •lesion seen on MRI in the CS, and
- •willing to give written informed consent.
排除标准
- •Pregnant and lactating patients
- •Patients already being treated (including steroids)
结局指标
主要结局
SUVmax of the cavernous sinus lesions on FDG PET/CT
时间窗: From enrollment to the establishment of final diagnosis upto a period of three months
Standardized uptake value (SUV) will be calculated by drawing region of interest (ROI) in the cavernous sinus region both on the whole body and the dedicated brain image, while carefully excluding normal brain activity. If lesions in the bilateral cavernous sinuses will be present, SUVmax of both the lesions will be noted.
Number of patients with extracranial sites of involvement on FDG PET/CT
时间窗: From enrollment to the establishment of final diagnosis upto 3 months
次要结局
未报告次要终点
研究者
Rajender Kumar
Additional Professor
Post Graduate Institute of Medical Education and Research, Chandigarh