Comparing the efficacy of topical application of 5 percent MINOXIDIL ALONE vs topical SULFOTRANSFERASE (SULT1A1) enzyme booster followed by 5 percent MINOXIDIL in the treatment of androgenetic alopecia- A non blinded randomized control study among patients attending dermatology and cosmetology opd
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- assessed by measuring hair density, hair diameter, hair count per follicular unit, interfollicular distance, serial photographic assessment
研究概览
简要总结
A non blinded randomized control trial
Male patients with androgenetic alopecia of age between 18 and 45 years willing to take part in the study are included and split into two groups. one group will be advised to apply topical 5% minoxidil alone and other group will be advised to apply topical sulfotransferase(SULT1A1) enzyme booster followed by topical 5% minoxidil. after 6 months analysis will be done whether applying sulfotransferase(SULT1A1) enzyme booster prior to 5% minoxidil improves hair growth significantly.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 45.00 Year(s)（—）
- 性别
- Male
入选标准
- •Male patients having Androgenetic alopecia grade 2 to 5(Norwood Hamilton scale) Age between 18 years and 45 years Patients willing for the study, consent and follow up Patients not on any other treatment for androgenetic alopecia for past 6 months.
排除标准
- •Patients below 18 years and above 45 years.
- •Female patients having androgenetic alopecia.
- •Concomitant dermatological disorders on the scalp other than androgenetic alopecia, serious cardiovascular disease, hepatic diseases, renal diseases.
- •History of treatment with systemic or locally acting medication which may interfere with the study objectives, such as minoxidil, finasteride treatment in the past 6 months or treatment with other hair growth products in the past 6months Patients with unrealistic expectation.
结局指标
主要结局
assessed by measuring hair density, hair diameter, hair count per follicular unit, interfollicular distance, serial photographic assessment
时间窗: every month for 6 months
次要结局
- subjective satisfaction will be assessed by patients self assessment through the following set of questionnaries.(after 6 months)
研究者
Dr Ranjith kumar U
The Tamilnadu Dr. M.G.R. medical university, chennai