Investigation of antipruritic effect of oral nicotinamide in uremic patients
Phase 2
- Conditions
- remic pruritus.Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classifiedC00-D48
- Registration Number
- IRCT201202068940N1
- Lead Sponsor
- Jundishapur University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
known cases of end-stage renal disease patients treated with hemodialysis; ages between 18 and 60 years; At least 6 weeks history of pruritus; no systemic or topical treatment for the pruritus. Exclusion criteria: a known hypersensitivity to nicotinamide; suffering from other known skin diseases, liver disorders, metabolic disorders, any other condition except for CRD causing pruritus; any serious systemic disease; Usage of antihistamines or other anti-pruritus drugs in the last three months.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Attenuation of uremic pruritus. Timepoint: Four weeks. Method of measurement: By using a traditional Visual Analogue Scale (VAS) and a modified questionnaire method (pruritus score).
- Secondary Outcome Measures
Name Time Method