Feasibility of the modified mini-bronchoalveolar lavage techniques using a nasogastric suction catheter and polytetrafluoroethylene bronchoscopic suction catheter in diagnosing pneumonia: A pilot study

Phase 1

Completed

• Conditions: Patient with bilateral pneumonia requiring mechanical ventilation; mini-BAL, ventilator associated pneumonia

• Registration Number: TCTR20230713011
• Lead Sponsor: avamindradhiraj University, Bangkok

Brief Summary

Mini BAL using an NG tube and PETF bronchoscopic suction catheter provide higher diagnostic yield compared to tracheal aspirate and revealed more polymicrobial etiology of VAP than tracheal aspirate.

Detailed Description

Not available

Study Timeline

• Study Completion: 2022-11-30
• Study Start: 2023-07-13
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

(1) patients aged over 18 years old, (2) those who require mechanical ventilation, and (3) those clinically suspected of pneumonia and abnormal chest radiography images consistent with bilateral pneumonia.

Exclusion Criteria

(1) patients who required bronchoscopy examination; (2) those with a high intracranial pressure; (3) those with an increased risk of bleeding, such as low platelet count (<50,000 cells/cumm3) or coagulopathy with an international normalized ratio of >1.5; (4) those with pneumothorax; and (5) those with confirmed coronavirus disease 2019 infection.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
diagnostic yield D0 of procedure culture

Secondary Outcome Measures

Name	Time	Method
safety during and post procedure hypoxemia, arrhythmia, bleeding