Does a Prophylactic Clip Application Decrease IPPB(Immediate Postpolypectomy Bleeding) and DPPB(Delayed Postpolypectomy Bleeding) After Colonoscopic Removal for a Large Pedunculated Polyps (>1cm)?
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Asan Medical Center
- Enrollment
- 137
- Locations
- 1
- Primary Endpoint
- the occurrence of immediate post-polypectomy bleeding
Study Overview
Brief Summary
The aim of this study is to evaluate the efficacy of prophylactic clip application after colonoscopic removal for a large pedunculated polyp (> 1cm) in preventing immediate postpolypectomy bleeding (IPPB) and delayed postpolypectomy bleeding (DPPB).
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Prevention
- Masking
- None
Eligibility Criteria
- Ages
- 20 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Patients who have a large pedunculated polyp(>1cm) in the colon
Exclusion Criteria
- •Age under 20 years
- •Subjects who are taking anticoagulants
- •Subjects who have an abnormal coagulogram (platelet count, international normalized ratio, or activated partial thromboplastin time)
- •Subjects who have inflammatory bowel diseases
Arms & Interventions
endoclip
The group of patients who undergo prophylactic clip application after colonoscopic polypectomy of a large pedunculated polyp(>1cm).
Intervention: prophylactic clip application (Procedure)
no endoclip
The group of patients who do not undergo prophylactic clip application after colonoscopic polypectomy of a large pedunculated polyp(>1cm).
Outcomes
Primary Outcomes
the occurrence of immediate post-polypectomy bleeding
Time Frame: 1 day
At 1 day after endoscopic polypectomy, CBC will be done.
the occurrence of delayed post-polypectomy bleeding
Time Frame: 2 weeks
At 2 weeks after endoscopic polypectomy, history of hematochezia will be taken at outpatient clinic.
Secondary Outcomes
No secondary outcomes reported
Investigators
Kyung-Jo Kim
Clinical Associate Professor
Asan Medical Center