Neural Mobilization in Cervico-Brachial Neuralgia

Not Applicable

Completed

• Conditions: Cervico Brachialgia

• Registration Number: NCT06913062
• Lead Sponsor: Hopital Charles Nicolle

Brief Summary

This study aimed to compare the effectiveness of neural mobilization (NM) combined with conventional rehabilitation versus conventional rehabilitation alone in patients with chronic common cervico-brachial neuralgia (CBN), focusing on pain, cervical range of motion (ROM), functional disability, and psychological state.

A randomized controlled trial was conducted including patients with chronic CBN. They were randomized into two groups: control group received standard rehabilitation, while NM Group received the same treatment with additional NM techniques. Evaluations were conducted pre- and post-treatment, assessing pain, cervical ROM, functional disability and psychological state via the Beck Depression Inventory.

Detailed Description

Not available

Study Timeline

• Study Start: 2024-01-02
• Primary Completion: 2024-03-30
• Study Completion: 2024-03-30
• Study First Submitted: 2025-03-29
• Study First Submitted QC: 2025-03-29
• Status Verified: 2025-04
• Last Update Submitted: 2025-04-04
• Study First Posted: 2025-04-06
• Last Update Posted: 2025-04-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 32

Inclusion Criteria

• patients over 18 years old
• with chronic common CBN

Exclusion Criteria

• secondary CBN
• prior cervical surgery
• cervical trauma
• recent central or peripheral neurological conditions
• unstable cauda equina lesions,
• untreated tumors or infections.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
pain intensity	Outcome measures were collected at baseline prior to the intervention (T0) and at the end of the treatment period (T1).	Pain: was assessed using the Visual Analog Scale (VAS) which ranges from 0 (no pain) to 10 (maximal imaginable pain)

Secondary Outcome Measures

Name	Time	Method
mobility	Outcome measures were collected at baseline prior to the intervention (T0) and at the end of the treatment period (T1).	Joint mobility assessment: focused on both the qualitative and quantitative aspects of movement. Following active movement, the therapist conducts a passive evaluation to analyze the end-range of motion (ROM) and any associated pain
function	Outcome measures were collected at baseline prior to the intervention (T0) and at the end of the treatment period (T1).	Functional assessment: was performed using the Copenhagen Neck Functional Disability Scale (CNFDS) in its Arabic version. It is a self-administered questionnaire that measures functional disability levels in patients suffering from cervical pain. The CNFDS consists of 15 questions addressing various aspects of daily life, including headache, sleep quality, concentration, and psychosocial factors such as social interaction and emotional relationships. Scores on the scale range from 0 (no disability) to 30 (maximum disability)
depression	Outcome measures were collected at baseline prior to the intervention (T0) and at the end of the treatment period (T1).	Psychological evaluation: was conducted using the Beck Depression Inventory (BDI). The Arabic validated version of this inventory was used to gauge the psychological state of patients, providing a quantitative estimate of depressive symptoms. The BDI includes 21 items that describe specific behavioral manifestations of depression, rated on a scale from 0 to 3. The final score is interpreted in terms of depression severity: 0-9 indicates minor depression, 10-18 indicates mild depression, 19-29 indicates moderate depression, and 30-63 indicates severe depression

Trial Locations

Locations (1)

Charles Nicolle Hospital; 🇹🇳 Tunis, Tunisia