Skip to main content
MedPathMedPath Home
Clinical Trials/NCT05984979
NCT05984979
Recruiting
Not Applicable

The Daytime Circadian Rhythm in Exhaled Volatile Organic Compounds in People Living Without and With Type 1 and 2 Diabetes: an Exploratory Study

University of Bern1 site in 1 country60 target enrollmentAugust 7, 2023
Share to TwitterShare to FacebookShare to LinkedInShare to Reddit
ConditionsDiabetes Mellitus

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Diabetes Mellitus
Sponsor
University of Bern
Enrollment
60
Locations
1
Primary Endpoint
VOC Patterns over time as boxplots
Status
Recruiting
Last Updated
4 months ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

Exhaled volatile organic compounds will be measured during daytime with the goal to identifying circadian variability. The study incudes three subgroups: people without diabetes, people with type 1 diabetes, and people with type 2 diabetes. A total of 60 people will be recruited for the study.

Registry
clinicaltrials.gov
Start Date
August 7, 2023
End Date
June 30, 2026
Last Updated
4 months ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

VOC Patterns over time as boxplots

Time Frame: During the study procedure (approximately 8 hours)

Box plots from selected VOC peaks over time.

VOC Patterns over time as gallery plots

Time Frame: During the study procedure (approximately 8 hours)

Gallery plots (3D visualization of retention index, drift time, ion current) from selected VOC peaks over time.

Secondary Outcomes

  • Capillary blood glucose(During the study procedure (approximately 8 hours))
  • Correlation between VOCs in breath intestinal microbiota(day 1)
  • Correlation between VOCs in breath oral microbiota(day 1)
  • Correlation between VOCs and subgroups(day 1 or 8 hours)

Study Sites (1)

Loading locations...

Similar Trials

Completed
Not Applicable
Temporal Variation in Exhaled Volatile Organic Compounds in Esophageal Cancer PatientsEsophageal Cancer
NCT06453993Benaroya Research Institute46
Completed
Not Applicable
Analysis of Exhaled Breath by Biosensors in Adults With AsthmaAsthma
NCT00819676Catholic University of the Sacred Heart47
Recruiting
Not Applicable
Organic Compounds and Postoperative DelirumIdentify Postoperative Delirium Using Exhaled Gas Patterns
NCT05875220University of Virginia150
Suspended
Not Applicable
Identification of Breath Biomarkers in Head and Neck Squamous Cell CarcinomaOral Cavity Squamous Cell CarcinomaOropharyngeal Squamous Cell Carcinoma
NCT02156180Queensland Centre of Excellence for Head and Neck Cancer13
Terminated
Not Applicable
NanoSpectrometer Biomarker Discovery and Confirmation StudyLung Cancer
NCT03275688Johns Hopkins University332