Innovative cardiac MRI in growing high-risk populations to improve outcome

Completed

• Conditions: overgewicht en hypertensie patienten; cardiomyopathy; non-ischemic acquired heart disease; 10028593; 10012653

• Registration Number: NL-OMON47375
• Lead Sponsor: niversitair Medisch Centrum Groningen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 320

Inclusion Criteria

- age 18-40 years old
- no known cardiovascular disease
- no co-morbidity besides the primary studied risk factor
- informed consent.
- no cardiac history, <4h sports/week
- no smoking
- healthy, overweigthed (BMI >25), type 2 diabetes or hypertension

Exclusion Criteria

- contra-indication for MRI and or Gadolinium
- metalcontaining meterial inside the body
- smoking
- heart patient under treatment of a cardiologist
- claustrophobia
- pacemaker

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary endpoint is the validation of cardiac MRI cut-off values for<br /><br>cardiac volumes, dimensions, mass, T1 tissue values, and Strain results, in<br /><br>high risk populations. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary endpoints include better understanding of cardiac modifications<br /><br>accompanying HT, DM, and OB, and more accurate diagnosis of cardiomyopathy in<br /><br>these groups. </p><br>