Comparative Evaluation of Single and Multiple Session Photodynamic Therapy using Indocyanine Green as an Adjunct to Scaling and Root Planing on Gingival Crevicular Fluid MMP 8 levels in the Treatment of Chronic Periodontitis: A Split-Mouth Clinical and Biochemical Study.

Dr Samaleti Ashwini Sudhakar0 个研究点目标入组 19 人开始时间: 待定最近更新: 2021年11月24日

试验速览

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•1.Systemically healthy subjects aged between 18 to 60 years rendering informed consent to participate in the study.
•2.Subjects having at least 20 natural teeth with a minimum of three teeth in each quadrant.
•3.Subjects diagnosed with chronic periodontitis according to American Academy of
•Periodontology (AAP) classification 1999 16 with at least 30% sites examined having >3mm attachment loss with radiographic evidence of bone loss.
•4.Subjects having at least one tooth per quadrant with attachment loss >=3mm and probing depth >=4 mm with corresponding tooth in contralateral quadrant in maxilla or mandible with similar site characteristics separated by atleast one tooth.

•1.Subjects who have received any form of surgical or non-surgical periodontal therapy within the past 6 months.
•2.Subjects who have received antimicrobial and / or anti-inflammatory therapy within the past 3 months.
•3.Subjects with systemic disease such as diabetes mellitus, hypertension, bleeding disorders, uremia, anticoagulants, steroids and nutritional supplements.
•4.Subjects who are smokers and consume tobacco and betel nut in any form
•5.Pregnant women and lactating mothers.
•6.Subjects having teeth with endodontic -periodontal lesions.
•7.Subjects wearing orthodontic appliances.
•8.Subjects with untreated grossly carious and fractured teeth.
•9.Subjects with excessive functional loading.
•10.Subjects having teeth with overhanging restorations and ill-fitting prosthesis.
•11.Third molars.
•12.Teeth with furcation involvements will not be considered as study teeth.
•13.Allergy to Indocyanine Green/Sulphur Iodide.

发起方

Dr Samaleti Ashwini Sudhakar