Efficacy of thiamine in treatment of post-cardiac arrest patients: a randomized controlled pilot study

Phase 1

Completed

• Conditions: - post cardiac arrest adult medical patients. - unconsciousness; Post cardiac arrest patients

• Registration Number: TCTR20161226001
• Lead Sponsor: Faculty of Medicine, Prince of Songkla University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2016-12-26
• Study Completion: 2018-12-24
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

- Adults > 18 years old
- Post cardiac arrest patients with successful return of spontaneous circulation
- unconsciousness (Glasgow Coma Scores < 8)

Exclusion Criteria

- No informed consent from next of kins
- Palliative care patients
- Unconscious patients or vegetative patients before cardiac arrest
- Need thiamine treatments by physician

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
mortality 28 day death

Secondary Outcome Measures

Name	Time	Method
eurological outcome at hospital discharge cerebral performance catagories ,Brain marker at 72 hours S100B,Lactate at 24, 48 and 72 hours lactate levels