Comparison of short and long term complications of treatment with oral ibuprofen versus fluid restriction in preterm infants with patent ductus arteriosus .
Phase 2
- Conditions
- Patent Ductus Arteriosus.Patent ductus arteriosus
- Registration Number
- IRCT2013071113022N2
- Lead Sponsor
- Semann University of Medical Sciences-
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 38
Inclusion Criteria
All premature neonates with gestational age of less than 38 weeks:EKG with left axis deviation of prematurity:the neonates of having systolic murmur and bounding pulse .and the neonates with patent ductus arteriosus proved on echocardiography were included.
Exclusion criteria:
Those having other congenital heart disease than PDA:neonates with other congenital anomalies:neonates with clinical signs of congestive heart failure :the neonates of mothers taking nonsteroidal antiinflammatory agents during pregnancy
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Ductal Closure. Timepoint: First day-3rd day-3rd month-6 months. Method of measurement: Echocardiography.;Pulmonary hypertension. Timepoint: 1st day-3rd day-3rd month-6th month. Method of measurement: Echocardiography.
- Secondary Outcome Measures
Name Time Method Intraventricular hemorrhage. Timepoint: 1st week-1st month. Method of measurement: sonography.;Periventricular leukomalacia. Timepoint: 1st week-1st month. Method of measurement: sonography.;Retinopathy of prematuriity. Timepoint: At discharge. Method of measurement: Retinoscope.