跳至主要内容
临床试验/CTRI/2022/03/041152
CTRI/2022/03/041152招募中不适用

“Comparative Evaluation of 0.75% Hyperbaric Ropivacaine versus 0.5% Hyperbaric Bupivacaine for Elective Infraumbilical Surgeries : A randomised controlled study.â€

DEPARTMENT OF ANESTHESIA RAJENDRA INSTITUTE OF MEDICAL SCIENCES RANCHI JHARKHAND1 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2022年1月4日最近更新:

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
80
试验地点
1
主要终点
TIME FOR ONSET OF SENSORY BLOCKADE AT (T10) DERMATOME LEVEL, MAXIMUM SENSORY BLOCKADE ACHIEVED, TIME TO COMPLETE MOTOR BLOCKADE, TIME OF REGRESSION OF SENSORY BLOCKADE AND TIME TO REQUIREMENT OF RESCUE ANALGESIA

研究概览

简要总结

0.5% Hyperbaric bupivacaine is the commonly used drug for providing spinal anaesthesia. However, serious toxicities associated with it triggered the development of alternative local anaesthetics. Introduction of commercially prepared 0.75% hyperbaric ropivacaine opens up possibilities of an alternative drug for spinal anaesthesia with less toxic profile while curtailing the issue of possible contamination associated with self preparation of hyperbaric ropivacaine by addition of glucose. Considering the fact, that bupivacaine is cardiotoxic drug, we planned this study effects of 0.75% Ropivacaine versus 0.5 % Bupivacaine in spinal anesthesia in patients undergoing infraumbilical surgeries.

研究设计

研究类型
Interventional
分配方式
Computer generated randomization
盲法
Participant and Investigator Blinded

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • American Society of Anaesthesiologists (ASA) physical status 1 and 2 of Age group between
  • 60 years of age Undergoing elective infraumbilical surgeries.

排除标准

  • Patient refusal, Bleeding disorder, Neurological disease, Local skin infection, Allergy to study drugs, Back deformities, Raised intracranial pressure, Patients on anticoagulant or antiplatelet therapy and ASA physical status >2.

结局指标

主要结局

TIME FOR ONSET OF SENSORY BLOCKADE AT (T10) DERMATOME LEVEL, MAXIMUM SENSORY BLOCKADE ACHIEVED, TIME TO COMPLETE MOTOR BLOCKADE, TIME OF REGRESSION OF SENSORY BLOCKADE AND TIME TO REQUIREMENT OF RESCUE ANALGESIA

时间窗: UPTO 24 HOURS AFTER SURGERY

次要结局

  • Hemodynamic variations in both groups and Any adverse effects of the drugs used will be recorded

研究者

发起方
DEPARTMENT OF ANESTHESIA RAJENDRA INSTITUTE OF MEDICAL SCIENCES RANCHI JHARKHAND
申办方类型
Research institution and hospital

研究点 (1)

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