Cognitive Testing Online in Parkinson's Disease
- Conditions
- Parkinson Disease
- Interventions
- Other: Neurocognitive testing
- Registration Number
- NCT05025254
- Lead Sponsor
- McGill University
- Brief Summary
This is a feasibility and pilot study. Though large-scale online neurocognitive testing is increasingly being done in psychiatry, there are no such efforts in Parkinson's research. Thus a large part of this pilot study will be to demonstrate feasibility and reliability, and use this experience to develop a feasible protocol for ongoing research. The specific short-term objectives are:
1. To establish the feasibility of performing large-scale deep cognitive phenotyping using online cognitive testing.
2. To demonstrate that online neurocognitive testing is valid and reliable in a smaller sample of locally recruited participants tested both in-lab and online.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 1000
- diagnosis of Parkinson's disease by neurologist or healthy individual with no diagnosis of any neurological illness
- Psychotic spectrum disorders, active uncontrolled depression, advanced dementia (i.e. needing assistance with daily activities such as dressing or bathing), major stroke, major head injury, epilepsy requiring anti-seizure medications
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Healthy controls Neurocognitive testing This is an observational study. The healthy control group will consist of participants who self-report that they do not have a diagnosis of Parkinson's disease PD patients Neurocognitive testing This is an observational study. The PD patient group will consist of participants who self-report that they have a diagnosis of Parkinson's disease
- Primary Outcome Measures
Name Time Method Completion rate of cognitive test set (feasibility) Measured once, as this is a cross-sectional study (time to complete cognitive tests is estimated to be 1.5 hours) Proportion of registered participants who complete all the cognitive testing.
- Secondary Outcome Measures
Name Time Method Reliability of web-based vs in-person executive function testing (Stroop test performance) Web-based and in-person testing will occur at two separate time points, at least 1 month apart and no more than 3 months apart Intraclass correlation coefficient for web-based vs. in-person performance on the Stroop test will be computed
Reliability of web-based vs in-person working memory testing (n-back test) Web-based and in-person testing will occur at two separate time points, at least 1 month apart and no more than 3 months apart Intraclass correlation coefficient for web-based vs. in-person performance on the n-back test will be computed
Reliability of web-based vs in-person reward processing testing Web-based and in-person testing will occur at two separate time points, at least 1 month apart and no more than 3 months apart Intraclass correlation coefficient for web-based vs. in-person performance on the probabilistic reward task will be computed
Reliability of web-based vs in-person visuospatial function testing (Trail making test performance) Web-based and in-person testing will occur at two separate time points, at least 1 month apart and no more than 3 months apart Intraclass correlation coefficient for web-based vs. in-person performance on the Trail making test will be computed
Reliability of web-based vs in-person declarative memory testing (recognition memory) Web-based and in-person testing will occur at two separate time points, at least 1 month apart and no more than 3 months apart Intraclass correlation coefficient for web-based vs. in-person performance on the image recognition test will be computed
Trial Locations
- Locations (1)
McGill University Health Centre
🇨🇦Montréal, Quebec, Canada