Comparison of long-term outcome of different epithelial transplantation techniques in treatment limbal stem cell deficiency

Completed

• Conditions: efficacy of different epithelial transplantation techniques in treatment limbal stem cell deficiency (LSCD); Simple Limbal Epithelial Transplantation; Limbal stem cell deficiency; Cultivated Limbal Epithelial Transplantation; Cultivated Oral Mucosal Epithelial Transplantation

• Registration Number: TCTR20220913002
• Lead Sponsor: /A

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2022-08-31
• Study Start: 2022-09-13
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 112

Inclusion Criteria

patients with LSCD who underwent Cultivated Limbal Epithelial Transplantation (CLET) or Simple Limbal Epithelial Transplantation (SLET) or Cultivated Oral Mucosal Epithelial Transplantation (COMET) at Department of Ophthalmology, Siriraj hospital between October 2007 and March 2022

Exclusion Criteria

patients with less than 6 months follow-up

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
compare long-term outcome of different epithelial transplantation techniques in treatment limbal stem cell deficiency (LSCD) median follow-up time was 70 (IQR 30-135.75) months Survival rate

Secondary Outcome Measures

Name	Time	Method
risk factor associated with the failure of outcome median follow-up time was 70 (IQR 30-135.75) months Risk factor analysis