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Hürthle Cell Carcinoma and Follicular Thyroid Carcinoma

Completed
Conditions
Huerthle Cell Carcinoma
Registration Number
NCT05968196
Lead Sponsor
The Catholic University of Korea
Brief Summary

The goal of this retrospective study is to evaluate in patients with HCC and FTC who underwent lobectomy. The main questions it aims to answer are:

* The necessity of completion thyroidectomy based on the clinicopathological characteristics

* Prognosis Participants underwent thyroid lobectomy Researchers compared HCC and FTC groups to see the prognosis after lobectomy.

Detailed Description

Background The prognosis of Hürthle cell carcinoma (HCC) and follicular thyroid carcinoma (FTC) is poorly understood. These types of cancers are usually confirmed after diagnostic lobectomy. We aimed to evaluate the clinicopathological characteristics and prognoses of patients with HCC and FTC who did not undergo completion thyroidectomy.

Materials and Methods We screened 221 patients diagnosed with FTC or HCC after thyroid lobectomy at Yonsei Severance Hospital between January 2000 and December 2020. After excluding patients who underwent complete thyroidectomy, 184 patients with FTC and 37 patients with HCC were included.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
221
Inclusion Criteria
  • Follicular thyroid carcinoma
  • Hurthle cell carcinoma
  • Lobectomy
Exclusion Criteria
  • Completion thyroidectomy
  • Total thyroidectomy

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Disease-free survival (DFS)From January 2000 to March 2023

a comparison of disease-free survival (DFS) between FTC and HCC groups

Secondary Outcome Measures
NameTimeMethod
TNM stageFrom January 2000 to March 2023

a comparison of TNM stage between FTC and HCC groups

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