Clinicopathological Characteristics of Hürthle Cell Carcinoma and Follicular Thyroid Carcinoma Without Completion Thyroidectomy
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 221
- Primary Endpoint
- Disease-free survival (DFS)
Study Overview
Brief Summary
The goal of this retrospective study is to evaluate in patients with HCC and FTC who underwent lobectomy. The main questions it aims to answer are:
- The necessity of completion thyroidectomy based on the clinicopathological characteristics
- Prognosis Participants underwent thyroid lobectomy Researchers compared HCC and FTC groups to see the prognosis after lobectomy.
Detailed Description
Background The prognosis of Hürthle cell carcinoma (HCC) and follicular thyroid carcinoma (FTC) is poorly understood. These types of cancers are usually confirmed after diagnostic lobectomy. We aimed to evaluate the clinicopathological characteristics and prognoses of patients with HCC and FTC who did not undergo completion thyroidectomy.
Materials and Methods We screened 221 patients diagnosed with FTC or HCC after thyroid lobectomy at Yonsei Severance Hospital between January 2000 and December 2020. After excluding patients who underwent complete thyroidectomy, 184 patients with FTC and 37 patients with HCC were included.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Retrospective
Eligibility Criteria
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Follicular thyroid carcinoma
- •Hurthle cell carcinoma
- •Lobectomy
Exclusion Criteria
- •Completion thyroidectomy
- •Total thyroidectomy
Outcomes
Primary Outcomes
Disease-free survival (DFS)
Time Frame: From January 2000 to March 2023
a comparison of disease-free survival (DFS) between FTC and HCC groups
Secondary Outcomes
- TNM stage(From January 2000 to March 2023)
Investigators
Kwangsoon Kim
Assistant Professor
The Catholic University of Korea