Association study between single nucleotide polymorphisms of glycogen synthase kinase -3 (GSK-3) and a specific group of patients with diagnostic conversion from depression to bipolar disorder and finally to dementia.
Not Applicable
Recruiting
- Conditions
- Depression, bipolar disorder, dementia
- Registration Number
- JPRN-UMIN000041145
- Lead Sponsor
- Oita University Faculty of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 600
Inclusion Criteria
Not provided
Exclusion Criteria
Subjects who are judged as inappropriate one at the discretion of the doctors.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Genotypic and allelic distributions of GSK-3 single nucleotide polymorphism. To compare the group of dementia with the past history of mood disorder (depression or bipolar disorder) and the group of dementia without.
- Secondary Outcome Measures
Name Time Method Genotypic and allelic distributions of GSK-3 single nucleotide polymorphism. To investigate genetic association of the group of patients whose diagnosis is not changed from depression to bipolar disorder.