se of tablets of Pregabalin and Clonidine to give safer general anesthesia to patients during gall bladder removal operations.
Phase 3
- Conditions
- Health Condition 1: - Health Condition 2: K801- Calculus of gallbladder with othercholecystitis
- Registration Number
- CTRI/2020/09/027926
- Lead Sponsor
- Department Of Anesthesiology and Critical Care JNMCH AM
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Prior Written informed consent.
Patients scheduled for Laparoscopic Cholecystectomy.
Patients with ASA grade 1 and 2.
Exclusion Criteria
Patient refusal or Unco-operative patients
History of chronic pain/ neuropathy.
Patients with co-existing cardiac disease, asthma, severe renal or hepatic dysfunction.
Anticipated difficult intubation.
Hypersensitivity reaction.
Psychiatric and neurological diseases.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To assess and compare the changes in heart rate, systolic, diastolic and mean systemic arterial blood pressureTimepoint: Before induction <br/ ><br>After intubation1min,5min,10min <br/ ><br>After creation of pneumoperitonium at 15min,30min,45min <br/ ><br>10min after release of pneumoperitonium <br/ ><br>10min after extubation
- Secondary Outcome Measures
Name Time Method To assess and compare post operative pain. <br/ ><br>To assess the intra operative and post operative analgesic requirement. <br/ ><br>To evaluate and compare post operative nausea and vomiting. <br/ ><br>Timepoint: RSS at whendrug is given,1hour,2hours,4hours <br/ ><br>VAS at 30min after extubation,60min after extubation,4hours after extubation, 8hours after extubation,12hours after extubation <br/ ><br>POST OP NAUSEA/VOMITTING yes 0r no <br/ ><br>RESCUE ANALGESIA yes 0r no