Validation of a Diagnostic Score for Encephalitis to Assess the Risk of Autoimmune Origin
概览
- 阶段
- 不适用
- 干预措施
- 未指定
- 疾病 / 适应症
- Autoimmune Encephalitis
- 发起方
- Hospices Civils de Lyon
- 入组人数
- 350
- 试验地点
- 1
- 主要终点
- Validation of a diagnostic score for encephalitis to assess the risk of autoimmune origin.
- 状态
- 进行中（未招募）
- 最后更新
- 2年前
概览
简要总结
The investigators wish to test a diagnostic risk score for autoimmune encephalitis in case of encephalitis, previously validated by two American teams, in a retrospective analysis, according to the clinical and paraclinical data available in our database of the Reference Centre for Autoimmune Encephalitis and Paraneoplastic Neurological Syndromes of Professor Honnorat for patients with NMDAr, anti LGi1, anti CASPR2, anti GABAbr and anti GAD antibodies.
研究者
入排标准
入选标准
- •Age \> 18 years old
- •Patient with a definite auto-immune encephalitis (Graus and al. 2016)
排除标准
- •Uncomplete data in acute phase
- •Patient with several antibodies
- •Opposition
结局指标
主要结局
Validation of a diagnostic score for encephalitis to assess the risk of autoimmune origin.
时间窗: At baseline
Comorbidities assessed by the Charlson score
Mode of onset of disease
时间窗: At baseline
Results of antineuronal antibodies in CSF
时间窗: At baseline
Results of antineuronal antibodies in serum
时间窗: At baseline
Symptoms in the acute phase
时间窗: At baseline
Results of lumbar puncture
时间窗: At baseline