Efficacy of Fibrin Sealant to Reduce the Amount of Postoperative Drain in Patients With Harmonic Scalpel-assisted Total Thyroidectomy With Anterior Compartment Neck Dissections
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 78
- 试验地点
- 1
- 主要终点
- Postoperative Drainage Amount
研究概览
简要总结
Fibrin sealant has been studied to reduce post-thyroidectomy drain and hospital stay as well. However, no strong evidence from well-designed clinical trials is available. Harmonic scalpel is a ultrasonic vibrating scissors which makes it easy to cut and coagulate the tissues, thus reducing op time and postoperative drain, which is important to minimize hospital stay. The investigators hypothesized that fibrin sealant combined with harmonic scalpel-assisted procedure could guarantee no-drain postoperative care in total thyroidectomy with anterior compartment neck dissection.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •proven thyroid carcinoma
- •Thyroidectomy with anterior compartment neck dissection
排除标准
- •No use of harmonic scalpel during surgery
- •coagulation abnormality
- •refuse to participate
研究组 & 干预措施
Fibrin sealant
usage of fibrin sealant after surgery
干预措施: Usage of Fibrin sealant (Drug)
Fibrin sealant
usage of fibrin sealant after surgery
干预措施: Thyroidectomy (Procedure)
Control
No usage of fibrin sealant
干预措施: Thyroidectomy (Procedure)
结局指标
主要结局
Postoperative Drainage Amount
时间窗: serial measurement from 1day to 4day after surgery
method : measurement of drainage fluids from negative suction system every 8 hr until daily total amount reduces under 20mL
次要结局
未报告次要终点