Study of disease response in patients of Cancer of Cervix treated with a new technique of delivering radiation(Intensity Modulated Radiation Therapy)

Phase 3

• Conditions: Health Condition 1: null- Carcinoma Cervix

• Registration Number: CTRI/2017/11/010438
• Lead Sponsor: Jawaharlal Institute of Postgraduate Medical Education and Research

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: Closed to Recruitment of Participants
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

1.All biopsy-proven patients of carcinoma cervix

2.FIGO Stages 1b2-IVa

Exclusion Criteria

1.Patients with an ECOG Performance Status >2

2.Poor renal function tests (Serum Creatinine >1.2mg/dL)

3.Patient who had undergone previous pelvic surgery or irradiation

4.Patients with second malignancy

5.Patients <18 years old

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To calculate the proportion of patients achieving complete tumor response among patients with carcinoma cervix stages IB2-IVA receiving IMRT in our department.Timepoint: To calculate the proportion of patients achieving complete tumor response among patients with carcinoma cervix stages IB2-IVA receiving IMRT in our department 6 months from completion of treatment.

Secondary Outcome Measures

Name	Time	Method
1.To determine the proportion of patients developing selected acute and late toxicities <br/ ><br>2.To evaluate the association of disease, dose and host-related factors with tumor response and selected toxicities <br/ ><br>Timepoint: The toxicities will be documented upto 6 months after completion of treatment.