An Open Randamised Controlled Clinical study to compare and evaluate the effectiveness of ‘ Arka Taila’ verses Clobetasol Propionate cream on Vicharchika with special reference to Eczema.
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 70
- 试验地点
- 1
- 主要终点
- to evaluate subject for subjective symptoms like pidika,shyavavarnata, bahustrava and kandu and objective assessment for reducing the area of lesions in group of arka taila.
研究概览
简要总结
INTRODUCTION:
Ayurveda is one of the ancient health care system. Ayurveda promotes specific lifestyle changes and natural treatments to restore harmony between the body, mind, spirit and environment. Ayurveda is a holistic tradition and way of life that can assist each of us in claiming and celebrating our ability for wellness. One of the branch of Ayurveda, is Agadtantra .
Agadtantra & Vishachikitsa specializes in the management and prevention of dermatological disorders. Agadtantra focuses on: Hair fall, Dandruff, Pimples, Acne, Skin conditions like dry skin, skin colour changes, itching etc, Insect bites and stings, Spider and Scorpion poisoning, Chronic snake poisoning, Acute and chronic food poisoning, Non healing ulcer with history of poisoning, Chronic and acute skin disorders with history of poisoning, Chronic or cumulative toxicity.
In Ayurveda, all skin diseases are described under the heading of Kushtha. Further it is divided into Mahakushtha and Kshudrakushtha[1] . Vicharchika is one of the kshudrakushtha.
Vicharchika is Kapha dominant Vyadhi. Kaphghna, Ruksha, Kledaghna, Raktashodhaka, treatment is expected. Arka taila [3] described under ancient texts have Gunas which are opposite to the Vyadhi Doshas, the vitiated Doshas of Vicharchika which are described above are mostly Kaphaj and Arka taila contains Ushna and Tikshna Guna so by opposing the above Doshas the diseases are trying to be treated.
A similar clinical presentation in modern dermatology is seen in Eczema. It is a medical condition in which patches of skin become rough and inflamed with blisters which cause itching and bleeding. India records more than 10 million cases of Eczema every year, with a prevalence rate of about 9.1%.
Arka Taila contains only three drugs viz. Arka Patra (Calotropis procera), Haridra (Curcuma longa) and Sarshapa Taila(Brassica campestris). Arka Taila was prepared by general method of preparation of Taila Kalpana till the Kharapaka stage. Arka Taila has Katu and Tikta Rasa, Ruksha, Laghu, Tikshna Guna, Ushna Veerya, Katu Vipaka, and Kapha-Vatashamaka properties.
NEED OF STUDY:
India records more than 10 million cases of Eczema every year, with a prevalence rate of about 9.1%.
To reduce the prevalence of eczema (Vicharchika) .
To reduce the use of topical steroids like clobetasol propionate cream 0.5%.
To enhance the use of ayurvedic Drugs.
NUMBER OF PATIENTS :
Group A - study group - 35 patients will apply arka taila.
Geoup B - control group - 35 patients will apply clobetasol propionate cream.
INVESTIGATION:
CBC, ESR, LFT, RFT, BSL, lipid profile, HbsAg, VDRL
SUMMARY AND CONCLUSION:
The work will be summarized to make final conclusions Observations of results will be concluded with statistical analysis under the heading ‘Conclusion’ with explanation at the end of whole research.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Open Label
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patient with sign and symptoms of Vicharchika like Kandu, pidika , shyavavarna and , bahustrava all over body.Understanding and being willing to sign the informed consent form.
排除标准
- •1.Pregnancy and lactating women.
- •2.Dry Eczema.
- •3.Immuno-compromised patients like AIDS (HIV positive), HbsAg positive etc.
- •4.Person With Severe Disorder Like CA, liver disorder, renal or cardiac problems, bed ridden due to chronic illness, patient having uncontrolled DM/HTN.
- •5.Any complication arising during the treatment of any patient discontinuing the treatment will be excluded.
- •6.Patient with other deliberating disease like TB/SLE.
- •7.Patient on medication as, Chemotherapy or Radiotherapy.
- •9.Mentally retarded patient and psychologically disturbed.
结局指标
主要结局
to evaluate subject for subjective symptoms like pidika,shyavavarnata, bahustrava and kandu and objective assessment for reducing the area of lesions in group of arka taila.
时间窗: 1 month
To evaluate subject subjective symptoms like pidikal, shyavarna, bahustrava and kandu and objective assessment for reducing the area of lesion in group of clobetasol propionate cream.
时间窗: 1 month
To compare the subjective symptoms like pidika, shyavarna, bahustrava and kandu and objective assessment for reducing the area of lesion between the two groups
时间窗: 1 month
次要结局
- 1. to assess the possidble mode of action of arka tail.(2. To reduce the use of steroidal ointments.)