Skip to main content
Clinical Trials/NCT02218983
NCT02218983
Unknown
Not Applicable

The Prognostic Value of Limited Transthoracic Echocardiogram (LTTE) During Trauma Resuscitation

Riverside University Health System Medical Center1 site in 1 country110 target enrollmentJune 2014

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Patients Who Are in Shock and Intubated in the Trauma Bay (TB)
Sponsor
Riverside University Health System Medical Center
Enrollment
110
Locations
1
Primary Endpoint
length of stay in the intensive care unit
Last Updated
9 years ago

Overview

Brief Summary

Primary caregiver thoracic ultrasound (U/S) is a skill which is growing in utility in critical care. First introduced for volume assessment in nephrology and cardiology, it is now being researched in emergency and critical care. Data is still evolving in its use in initial trauma evaluation. Inferior vena cava (IVC) diameter correlates with outcome in trauma, but utility of its measurement on U/S in the emergency department still has some controversy. In trauma specifically, small studies suggests benefit to the use of U/S to predict volume status, and most of these data are from one author. It is not known if this can be applied more broadly. The prognostic value of findings on limited transthoracic echocardiogram (LTTE, SonoSite Ultrasound) has been studied in several small studies, and only one small randomized controlled trial has proven benefit to its use. Due to inter-rater reliability and the fact that all reports on credentialing of thoracic ultrasound use in the trauma bay are from one group, it is not known if it can be applied to all trauma populations.

Research question:

Does LTTE (SonoSite Ultrasound) predict mortality, emergency surgery, intensive care unit (ICU) stay, hospital stay, time on ventilator, number of transfusions, or renal failure as well as or better than other methods of organ perfusion?

Hypotheses:

  1. Use of LTTE is associated with improved outcomes (less organ failure, decreased hospital and ICU stays, transfusions, and mortality).
  2. LTTE predicts mortality, emergency surgery, ICU stay, hospital stay, time on ventilator, number of and transfusions better than other methods of organ perfusion (tachycardia, hypotension, lactate, lactate clearance, creatinine, base deficit).
Registry
clinicaltrials.gov
Start Date
June 2014
End Date
June 2018
Last Updated
9 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Aron Depew, MD

Principal Investigator

Riverside University Health System Medical Center

Eligibility Criteria

Inclusion Criteria

  • Patients arriving to trauma bay aged 18 or higher
  • Hypotensive (systolic blood pressure (SBP) \< 90 mmHg or mean arterial pressure (MAP) \< 65, on 2 measurements)
  • Respiratory failure (requiring mechanical ventilation)

Exclusion Criteria

  • Unable to draw blood before transfusion or fluid challenge
  • Patient arrests within 10 minutes of arrival
  • Note: If inferior vena cava (IVC) not visible on ultrasound (U/S), pt will go to non-IVC group.

Outcomes

Primary Outcomes

length of stay in the intensive care unit

Time Frame: length of stay in the intensive care unit, not to exceed 30 days

Secondary Outcomes

  • mortality (death)(mortality (death) during hospital stay, not to exceed 30 days)

Study Sites (1)

Loading locations...

Similar Trials