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临床试验/NCT03740685
NCT03740685Unknown不适用

Changes in High Sensitive C Reactive Protien With Different Treatment Modalities in Acute Pancreatitis

Assiut University1 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2018年11月9日最近更新:
适应症

试验速览

阶段
不适用
入组人数
80
试验地点
1
主要终点
Serum Amylase

研究概览

简要总结

changes in high sensitive C reactive protien with different treatment modalities in acute pancreatitis

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 75 Years(Adult, Older Adult)
性别
All
接受健康志愿者
否

入选标准

  • •Age>=18 years
  • •Diagnosis of acute pancreatitis confirmed by at least 2 of the following:
  • •Typical epigastric abdominal pain
  • •Elevation amylase/lipase >3 times upper limit normal and/or
  • •Confirmatory findings on cross-sectional imaging
  • •Enrollment within 8 hours of presentation

排除标准

  • •Class II or greater NYHA heart failure
  • •Oxygen dependent COPD
  • •Chronic kidney disease>stage 2
  • •Existing necrosis on abdominal CT
  • •Organ dysfunction prior to enrollment
  • •Acute respiratory distress syndrome
  • •Malignancy not in remission for at least 5 years
  • •Active drug use
  • •Known allergy to dexamethasone
  • •Altered mental status
  • •Insulin-requiring diabetes
  • •Abdominal surgery within 60days

结局指标

主要结局

Serum Amylase

时间窗: 72hours

Level of Serum Amylase expected to be changed with different lines of treatment and will be compaered

High sesitive C reactive protien

时间窗: 72hours

Level of High sesitive C reactive protien expected to be changed with different lines of treatment and will be compaered

Serum Lipase

时间窗: 72hours

Level of Serum Lipase expected to be changed with different lines of treatment and will be compaered

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Mahmoud Abdelhamed

principal investigator

Assiut University

研究点 (1)

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