Exploring the long-term impact of early life adversity on the (anti-)social brai

• Conditions: Vulnerability to stress-related antisocial disorders; F91; Conduct disorders

• Registration Number: DRKS00016359
• Lead Sponsor: Zentralinstitut für seelische Gesundheit

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 2018-11-01
• Study Start: 2019-01-17
• Study Completion: 2021-12-01
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 256

Inclusion Criteria

participants of the Mannheim Study of Children at Risk

Exclusion Criteria

metal implants or other MRI contraindications

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Effects of early adversity and protective factors on brain morphology and function implicated in the processing of social information. Specifically, we will investigate: 1) real-life quantitz and quality of social interactions via smartphone, 2) brain volume, surface area and cortical thickness, 3) BOLD response during the following tasks: empathy, emotion regulation, stop signal, reward, passive avoidance, cyberball and dictator game.

Secondary Outcome Measures

Name	Time	Method
not applicable