Prevent Cancer-Greenville: A Center for Cancer Prevention and Wellness Research Project
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 1,000
- 试验地点
- 1
- 主要终点
- Assess changes in physical activity by physical activity questionnaire
研究概览
简要总结
Prevent Cancer-Greenville was created to provide individuals with the opportunity to have their risk of developing cancer studied. Some individuals may be at a higher risk due to their personal lifestyle, family history and/or exposures. If subjects are found to be at high risk for developing a disease, they will be sent to a healthcare provider for further care.
详细描述
Participants' personal history, lifestyle behaviors and blood, urine, and cheek swab specimens will be used to detect changes or trends that might put them at risk for developing cancer. Some individuals may be at an above average risk of cancer due to lifestyle, family background, personal genetic makeup, or environmental exposures. This will be determined by a process called risk stratification. Risk stratification involves looking at all health-related aspects of a person, determining their individualized risk through screening, and educating them on measures to reduce potential for disease. Participants will complete a yearly health assessment which includes measurements for nutrition, activity, individual risk factors and body composition, including weight height and a special scale which measures fluid and fat.
研究设计
- 研究类型
- Observational
- 观察模型
- Ecologic Or Community
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •18 years or older
排除标准
- 未提供
结局指标
主要结局
Assess changes in physical activity by physical activity questionnaire
时间窗: Yearly follow up for 10 years
Physical activity will be assessed yearly a questionnaire based on physical activity recommendations from the U.S. Department of Health and Human Services.
Assess changes in alcohol use
时间窗: Yearly follow up for 10 years
Participants will be educated on healthy lifestyle habits and alcohol use will be assessed yearly.
Assess hereditary risk through family history review
时间窗: Yearly follow up for 10 years
Each participant's family history will be reviewed to make recommendations for screening or genetic testing based on National Comprehensive Cancer Network guidelines.
Assess changes in muscle mass by SOZO measurements
时间窗: Yearly follow up for 10 years
Body composition will be assessed yearly by measurements taken from the SOZO device which uses bioimpedance spectroscopy to measure muscle mass.
Assess changes in nutrition by nutrition questionnaire
时间窗: Yearly follow up for 10 years
Nutrition will be assessed yearly by a questionnaire based on nutrition recommendations from the American Institute for Cancer Research and the U.S. Department of Health and Human Services.
Assess changes in smoking habits
时间窗: Yearly follow up for 10 years
Participants will be educated on healthy lifestyle habits and smoking habits will be assessed yearly.
Assess lifetime breast cancer risk through the Tyrer-Cuzick version 8 breast risk evaluation tool
时间窗: Yearly follow up for 10 years
Participants' breast cancer risk will be assessed using the Tyrer-Cuzick breast cancer risk model. Participants will be referred to appropriate clinics if lifetime risk is greater than 20 percent.
Assess 5- year breast cancer risk through the GAIL breast risk evaluation tool
时间窗: Yearly follow up for 10 years
Participants' breast cancer risk will be assessed using the National Cancer Institute's GAIL model. Participants will be referred to appropriate clinics if GAIL 5 year risk is greater than 1.7 percent.
Assess changes in fat mass by SOZO measurements
时间窗: Yearly follow up for 10 years
Body composition will be assessed yearly by measurements taken from the SOZO device which uses bioimpedance spectroscopy to measure fat mass.
Early detection of malignancies through screening
时间窗: Yearly follow up for 10 years
Participants will be educated on screening recommendations by the American Cancer Society. Malignancies will be recorded yearly if found by recommended screenings.
次要结局
- Assess changes in quality of life by the 5-level EuroQol-5D version (EQ-5D-5L) questionnaire(Yearly follow up for 10 years)