Using Tea-based Mouthwash Relieve Stomatitis and Oral Ulcers
- Conditions
- Stomatitis
- Interventions
- Combination Product: mouthwash with tea
- Registration Number
- NCT05010928
- Lead Sponsor
- Chang Gung Memorial Hospital
- Brief Summary
The aim of this study is to use a tea-based mouthwash to relieve pain and discomfort in patients with stomatitis and ulcers.
- Detailed Description
The objective of this study is to use tea as a base, supplemented with licorice to reduce bitterness and astringency, to make mouthwash, and use tea's antioxidant and anti-inflammatory properties to relieve the pain and discomfort of stomatitis and ulcer patients. This study will observe the difference between saliva and oral mucosal cells before and after treatment, to find the mechanism of effective treatment of stomatitis.
Recruitment & Eligibility
- Status
- NOT_YET_RECRUITING
- Sex
- All
- Target Recruitment
- 100
age over 20 years old, male or female
patients with oral cavity cancer, oropharyngeal cancer, and active bacterial infection.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- FACTORIAL
- Arm && Interventions
Group Intervention Description Tea mouthwash group mouthwash with tea -
- Primary Outcome Measures
Name Time Method Xerostomia questionnaire (XQ) 4 weeks Questionnaires for symptoms relief of dry mouth
Xerostomia Inventory (XI) 4 weeks A multi-item approach to measuring dry mouth
- Secondary Outcome Measures
Name Time Method Rate of oral mucosa cells with angiotensin-converting enzyme 2 (ACE2) staining (+) 4 weeks Immunohistochemistry stain for ACE2 protein
Related Research Topics
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Trial Locations
- Locations (1)
Chiayi chang Gung Memorial Hospital
🇨🇳Chiayi City, Taiwan