NCT00786370已完成4 期
Dexmedetomidine vs. Propofol for Monitored Anesthesia Care During Cataract
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 24
- 试验地点
- 1
- 主要终点
- To compare select cardiorespiratory effects of dexmedetomidine sedation to those of propofol sedation in patients undergoing cataract surgery.
研究概览
简要总结
The use of dexmedetomidine in cataract surgery is still limited and to date only one study has examined anesthetic technique in this patient population. This pilot study will therefore compare the use of dexmedetomidine and propofol in subjects undergoing cataract surgery. The primary endpoint will be based on simple cardiorespiratory measures often associated with complications from sedation as well as assessment of the achieved sedation by the attending anesthesiologist and surgeon.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Normal renal function
- •No chronic use of narcotics
- •Males or females age 18 or older
排除标准
- •Liver disease (Child Pugh classification 1-3)
- •History of chronic use of sedatives, narcotics, alcohol or illicit drugs or allergy to any the study medications
- •History of 1st and 2nd degree heart block (not paced)
- •Any patient with EF < 30%
- •Patients with active seizure history
- •Pregnant patients (women of child bearing potential will have a preoperative pregnancy test as is standard of practice)
研究组 & 干预措施
Propofol
Active Comparator
干预措施: Propofol (Drug)
Dexmedetomidine
Experimental
干预措施: dexmedetomidine (Drug)
Dexmedetomidine
Experimental
干预措施: Dexemedetomidine (Drug)
结局指标
主要结局
To compare select cardiorespiratory effects of dexmedetomidine sedation to those of propofol sedation in patients undergoing cataract surgery.
时间窗: 1 day
次要结局
未报告次要终点
研究者
研究点 (1)
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