Local Anesthesia in Molar Teeth With Molar Incisor Hypomineralization

Not Applicable

Completed

• Conditions: Molar Incisor Hypomineralization
• Interventions: Diagnostic Test: Evaluation of cold test; Diagnostic Test: Evaluation of electrical pulp test; Diagnostic Test: Evaluation of pain during the treatment

• Registration Number: NCT04061096
• Lead Sponsor: Didem Sakaryali

Brief Summary

To compare responses to electrical pulp test (EPT) and cold test among molar incisor hypomineralization (MIH)-effected and not MIH-effected carious teeth before and after administration of local anesthesia for caries removal.

Detailed Description

Fifty carious permanent first molar teeth (25 MIH-effected, 25 not MIH-effected) were included. Firstly, radiographic caries depth, International Caries Detection and Assessment System (ICDAS) codes and MIH levels of teeth were recorded. Then, during the treatment, EPT and cold test were performed before and after the administration of local anesthesia. Visual Analog Scale for Pain was used to evaluate cold test and pain during treatment. When interpreting results, significancy level was stated for the values of p\<0.05.

Study Timeline

• Study Start: 2014-09-01
• Primary Completion: 2018-05-01
• Study Completion: 2018-05-01
• Status Verified: 2019-08
• Study First Submitted: 2019-08-10
• Study First Submitted QC: 2019-08-16
• Last Update Submitted: 2019-08-16
• Study First Posted: 2019-08-19
• Last Update Posted: 2019-08-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 38

Inclusion Criteria

• Healthy participants

Exclusion Criteria

• Not being cooperative during treatment procedure

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
MIH-effected carious first permanent molar teeth	Evaluation of electrical pulp test	MIH-effected carious permanent first molar teeth were well-demarcated white/yellow or brown/yellow enamel opacities which is a sign for hypomineralization and asymptomatic which meant to be without any spontaneous pain or pain during eating or drinking, percussion or palpation tenderness, formation of abcess or fistula.
MIH-effected non-carious first permanent molar teeth	Evaluation of pain during the treatment	MIH-effected teeth were carious permanent first molar teeth with well-demarcated white/yellow or brown/yellow enamel opacities which is a sign for hypomineralization and did not have any sign of caries.
not MIH-effected non-carious first permanent molar teeth	Evaluation of cold test	not any signs of being caries or hypomineralization.
not MIH-effected non-carious first permanent molar teeth	Evaluation of electrical pulp test	not any signs of being caries or hypomineralization.
MIH-effected carious first permanent molar teeth	Evaluation of pain during the treatment	MIH-effected carious permanent first molar teeth were well-demarcated white/yellow or brown/yellow enamel opacities which is a sign for hypomineralization and asymptomatic which meant to be without any spontaneous pain or pain during eating or drinking, percussion or palpation tenderness, formation of abcess or fistula.
not MIH-effected carious first permanent molar teeth	Evaluation of cold test	The carious not MIH-effected teeth were only carious without any hypomineralize areas and asymptomatic which meant to be without any spontaneous pain or pain during eating or drinking, percussion or palpation tenderness, formation of abcess or fistula.
not MIH-effected carious first permanent molar teeth	Evaluation of pain during the treatment	The carious not MIH-effected teeth were only carious without any hypomineralize areas and asymptomatic which meant to be without any spontaneous pain or pain during eating or drinking, percussion or palpation tenderness, formation of abcess or fistula.
MIH-effected carious first permanent molar teeth	Evaluation of cold test	MIH-effected carious permanent first molar teeth were well-demarcated white/yellow or brown/yellow enamel opacities which is a sign for hypomineralization and asymptomatic which meant to be without any spontaneous pain or pain during eating or drinking, percussion or palpation tenderness, formation of abcess or fistula.
not MIH-effected carious first permanent molar teeth	Evaluation of electrical pulp test	The carious not MIH-effected teeth were only carious without any hypomineralize areas and asymptomatic which meant to be without any spontaneous pain or pain during eating or drinking, percussion or palpation tenderness, formation of abcess or fistula.
MIH-effected non-carious first permanent molar teeth	Evaluation of cold test	MIH-effected teeth were carious permanent first molar teeth with well-demarcated white/yellow or brown/yellow enamel opacities which is a sign for hypomineralization and did not have any sign of caries.
not MIH-effected non-carious first permanent molar teeth	Evaluation of pain during the treatment	not any signs of being caries or hypomineralization.
MIH-effected non-carious first permanent molar teeth	Evaluation of electrical pulp test	MIH-effected teeth were carious permanent first molar teeth with well-demarcated white/yellow or brown/yellow enamel opacities which is a sign for hypomineralization and did not have any sign of caries.

Primary Outcome Measures

Name	Time	Method
Electrical pulp test results	Time frame of electrical pulp test evaluation was aproximately 1 hour for each participant.	Electrical pulp test values at which patients felt sensitive were recorded.
Cold test results	Time frame of cold test evaluation was aproximately 1 hour for each participant.	Visual Analog Scale for Pain was used to evaluate the cold tests for before and after the local anesthesia. Visual analog scale was used to rate the sensitivity level of patients with 6 different faces representing different levels of pain from "0=no pain" to "10=unbearable pain".
Pain during the treatment	Pain during the treatment was evaluated for aproximately 1 hour for each participant.	Visual Analog Scale for Pain was used to evaluate the pain during the treatment. Visual analog scale was used to rate the sensitivity level of patients with 6 different faces representing different levels of pain from "0=no pain" to "10=unbearable pain".