Uroflowmetry Results and Vitamin D Levels

Completed

• Conditions: Lower Urinary Tract Symptoms; Vitamin D Deficiency; Calcium Deficiency

• Registration Number: NCT04405141
• Lead Sponsor: Umraniye Education and Research Hospital

Brief Summary

The investigators aimed to evaluate the relationship between LUTS and vitamin D with uroflowmetry parameters in female patients. They found no relation between vitamin D levels and LUTS in respect to uroflowmetry. However, in low vitamin D patients, Ca is related with urologic problems. The investigators believe that there is a need for studies emphasizing serum Ca levels in addition to vitamin D levels in patients with LUTS.

Detailed Description

This retrospective cohort study included 186 female patients who admitted to LUTS. Demographic characteristics, medical history, calcium (Ca) and vitamin D including laboratory studies and uroflowmetry results as maximum urine flow rate (Qmax), average urine flow rate (Qav), and voided volume (V) were recorded. Patients were divided into two groups according to age (18-50 and ≥51) and vitamin D levels (\<20 and ≥20).

Laboratory parameters, uroflowmetry results, were compared between groups.

The study was approved by the local ethics committee (approval#22/06/2018-09.29-54132726-000-14136). The study was conducted in accordance to the Helsinki Declaration and Good Clinical Practices Guidelines.

Study Timeline

• Study Start: 2017-01-01
• Primary Completion: 2017-12-30
• Study Completion: 2017-12-30
• Status Verified: 2020-05
• Study First Submitted: 2020-05-09
• Study First Submitted QC: 2020-05-26
• Study First Posted: 2020-05-28
• Last Update Submitted: 2020-05-29
• Last Update Posted: 2020-06-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 186

Inclusion Criteria

Clinical diagnosis of low urinary tract symptom

Exclusion Criteria

Urinary tract infection, Diabetes mellitus, Neurological disorder, Pregnancy Stone disease Other urinary system disorders.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Uroflowmetry Results	12 months	There was no significant relationship between age, creatinine, Qmax, Qav, V and vitamin D level (P\>0.05).

Secondary Outcome Measures

Name	Time	Method
Vitamin D Levels	12 months	The mean D vitamin level was 21.19ng/ml. D vitamin was \<20 ng/ml in %55.9 patients. There was no difference in the levels according to the age of all patients.