Acute Kidney Injury After Cardiac Surgery on CPB

Completed

• Conditions: Acute Kidney Injury; Congenital Heart Disease; Surgery; Child, Only; CBP

• Registration Number: NCT03513718
• Lead Sponsor: Centre Hospitalier Universitaire Vaudois

Brief Summary

The purpose of this retrospective study is to determine the incidence and severity of acute kidney injuries (AKI) after heart surgery on cardiopulmonary bypass (CPB) in the pediatric intensive care unit (PICU) in Lausanne, Switzerland.

Detailed Description

The investigators will review in a retrospective way, all patients aged between 0 and 16 years, admitted in the PICU after cardiac surgery on CPB from 01.01.2014 to 31.12.2016. They will asses for AKI. The first step is to determine the incidence and severity, the second step is to determine the risk factors for AKI and/or protecting factors.

Study Timeline

• Study Start: 2017-10-01
• Study First Submitted: 2018-04-09
• Study First Submitted QC: 2018-04-30
• Study First Posted: 2018-05-01
• Primary Completion: 2022-09-30
• Study Completion: 2023-09-05
• Status Verified: 2024-02
• Last Update Submitted: 2024-02-10
• Last Update Posted: 2024-02-13

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 250

Inclusion Criteria

• all pediatric patients (0-16 years) admitted to PICU after cardiac surgery with CPB.

Exclusion Criteria

• Preexisting kidney injury,
• no preoperative creatinine lab value

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Presence and severity of an AKI occurring during stay in the PICU	up to 3 month	Scoring AKI with pRiffle

Secondary Outcome Measures

Name	Time	Method
PICU stay and ventilation time	up to 3 month	correlation between AKI and invasive ventilation/duration and PICU stay
Persisting AKI after release from PICU according to RIFLE score	more than 3 month	After leaving ICU

Trial Locations

Locations (1)

CHUV; 🇨🇭 Lausanne, Vaud, Switzerland