CARDIAC ULTRASOUND IN ADDITION TO LUNG AND DIAPHRAGM ULTRASOUND AS A PREDICTOR OF SUCCESSFUL WEANING FROM MECHANICAL VENTILATION IN PATIENTS ADMITTED IN INTENSIVE CARE UNIT.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- To evaluate left atrial pressure (LAP) as a predictor of successful weaning from mechanical ventilation in ICU patients.
研究概览
简要总结
This is a prospective observational study, predicting successful weaning in mechanically ventilated patients admitted in ICU of Lok Nayak Hospital New Delhi who are undergoing spontaneous breathing trial by measuring left atrial pressure, change in velocity time integral to passive leg raise, E/A ratio , E/e’ ratio, lung ultrasound score and diaphragm thickness fraction by performing cardiac, lung and diaphragm ultrasound respectively, rapid shallow breathing index at specified time of spontaneous breathing trial . Following this patients will be extubated and assessed for success of weaning and the need of non invasive ventilation or reintubation for 24 hours by doing arterial blood gas analysis 1st and 6hours of post extubation.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •Age 18 years to 65 years
- •mechanical ventilation for minimum 48 hours and maximum 7 days.
排除标准
- •patients with history of neuromuscular disease 2.patients with history of diaphragmatic dysfunction
- •patients with chest tube in situ
- •patients with pneumothorax and pneumomediastinum 5.patients with chronic obstructive pulmonary disease 6.pregnant patients 7.patients with known heart failure 8.significant cardiac arrythmia.
结局指标
主要结局
To evaluate left atrial pressure (LAP) as a predictor of successful weaning from mechanical ventilation in ICU patients.
时间窗: 30minutes from spontaneous breathing trial
次要结局
- To evaluate change in velocity time integral to passive leg raise, peak early and peak atrial velocity trans mitral flow from pulsed wave doppler and early diastolic mitral annulus velocity based on tissue doppler imaging were measured(Lung ultrasound score as predictor of successful weaning from mechanical ventilation in ICU patients)
研究者
Dr MEENA K S
Maulana Azad Medical College